INACTIVATION OF PATHOGENS IN EX VIVO BLOOD PRODUCTS IN STORAGE BAGS USING VISIBLE LIGHT

WIPO Patent Application WO/2017/062260

A3

Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device (12) into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus (12) includes a control unit (18) that operates a light source (10) that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.

WO/2007/103010	APPARATUS FOR SUPPORTING AND DISINFECTING A HANDHELD INSTRUMENT AND/OR A PORTION OF THE USER'S HAND
WO/1996/014092	SYNERGISTIC BIOCIDAL COMBINATIONS
JPH0688585	INDUSTRIAL APPLICABILITY A method for aseptically filling a container and a system thereof.

ATREYA CHINTAMANI (US)
MACLEAN MICHELLE (GB)
ANDERSON JOHN G (GB)
MACGREGOR SCOTT J (GB)

PCT/US2016/054508

May 18, 2017

September 29, 2016

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US HEALTH (US)
THE UNIV OF STRATHCLYDE (GB)

A61L2/00; A61K41/00; A61L2/08

WO2000074731A1	2000-12-14
WO1999059645A1	1999-11-25

US20070009377A1	2007-01-11
US20040021089A1	2004-02-05
DE4209509C1	1993-06-03
EP1693072A1	2006-08-23
EP0457196A2	1991-11-21

DUNCAN, Sandon, M. (US)

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