Title:
INDAN DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1999/062867
Kind Code:
A1
Abstract:
Cardiac failure remedies containing as the active ingredient indan derivatives represented by general formula (I) or medicinally acceptable salts thereof, wherein R?1¿ is hydrogen, nitro, cyano, amino, C¿1?-C¿6? alkylcarbonylamino or the like; R?2¿ and R?3¿ are each independently C¿1?-C¿6? alkyl or the like; R?4¿ is hydroxyl or C¿1?-C¿6? alkylcarbonyloxy, or alternatively R?4¿ together with R?5¿ represents a bond or oxygen; R?5¿ is hydrogen, or alternatively R?5¿ together with R?4¿ represents a bond or oxygen; R?6¿ is hydrogen, hydroxyl, NR?7¿R?8¿ or the like; n is an integer of 0 to 4; X is C=O, CH¿2?, SO¿2? or NR?16¿; when X is C=O, CH¿2? or SO¿2?, Y is NR?17¿, while when X is NR?16¿, Y is C=O; when Y is NR?17¿, Z is absent, while when Y is C=O, Z is NR?18¿; and W is aryl, a lactam ring or the like.
Inventors:
OHRAI KAZUHIKO (JP)
TANIKAWA KEIZO (JP)
SATO MASAYUKI (JP)
YANAGIHARA KAZUFUMI (JP)
SHIGETA YUKIHIRO (JP)
YAMASHITA TORU (JP)
TANIKAWA KEIZO (JP)
SATO MASAYUKI (JP)
YANAGIHARA KAZUFUMI (JP)
SHIGETA YUKIHIRO (JP)
YAMASHITA TORU (JP)
Application Number:
PCT/JP1999/002935
Publication Date:
December 09, 1999
Filing Date:
June 02, 1999
Export Citation:
Assignee:
NISSAN CHEMICAL IND LTD (JP)
OHRAI KAZUHIKO (JP)
TANIKAWA KEIZO (JP)
SATO MASAYUKI (JP)
YANAGIHARA KAZUFUMI (JP)
SHIGETA YUKIHIRO (JP)
YAMASHITA TORU (JP)
OHRAI KAZUHIKO (JP)
TANIKAWA KEIZO (JP)
SATO MASAYUKI (JP)
YANAGIHARA KAZUFUMI (JP)
SHIGETA YUKIHIRO (JP)
YAMASHITA TORU (JP)
International Classes:
C07C233/44; C07C233/55; C07C235/34; C07C235/38; C07C235/78; C07C237/20; C07C237/22; C07C255/57; C07C255/60; C07C261/04; C07C275/40; C07C275/42; C07D207/335; C07D207/337; C07D209/14; C07D209/18; C07D213/38; C07D213/40; C07D213/56; C07D239/26; C07D295/135; C07D303/36; C07D303/38; C07D303/40; C07D303/46; C07D307/52; C07D307/54; C07D333/20; C07D333/24; C07D207/32; (IPC1-7): C07C235/38; C07D207/33; C07D209/16; C07D209/18; C07D213/56; C07D239/26; C07D295/12; C07D303/36; C07D307/52; C07D307/54; C07D333/20; C07D333/24; A61K31/13; A61K31/165; A61K31/17; A61K31/18; A61K31/335; A61K31/34; A61K31/38; A61K31/40; A61K31/44; A61K31/445; A61K31/495; A61K31/505; A61K31/535
Foreign References:
| JPH1087650A | 1998-04-07 |
Other References:
See also references of EP 1085009A4
Attorney, Agent or Firm:
Hanabusa, Tsuneo (Kandasurugadai 1-chome Chiyoda-ku Tokyo, JP)
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