Title:
INDANE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/032328
Kind Code:
A1
Abstract:
The present invention relates to an indane derivative, a preparation method therefor, and a pharmaceutical application thereof. Specifically, the present invention relates to a compound shown in formula (I), or a stereoisomer thereof, an aquo complex, a metabolite, a solvate, pharmaceutically accepted salt, cocrystal or a prodrug, and preparation methods of the above; the present invention further relates to a pharmaceutical composition, and pharmaceutical applications of a compound and the pharmaceutical composition of the present invention, and in particular, to an application as an agonist of a GPR40 receptor (G protein-coupled receptor), definitions of substituents in formula (I) being identical with those in the specification.
Inventors:
ZHANG CHEN (CN)
HE PING (CN)
WEI YONGGANG (CN)
HE PING (CN)
WEI YONGGANG (CN)
Application Number:
PCT/CN2014/085848
Publication Date:
March 12, 2015
Filing Date:
September 03, 2014
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07C317/18; A61K31/192; A61K31/341; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P13/12; A61P25/00; C07C315/04; C07D307/20
Foreign References:
| CN102421739A | 2012-04-18 | |||
| CN101282934A | 2008-10-08 | |||
| EP1916234A1 | 2008-04-30 |
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
北京三友知识产权代理有限公司 (CN)
北京三友知识产权代理有限公司 (CN)
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