INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP

Title:

INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP

Document Type and Number:

WIPO Patent Application WO/1996/038420

Kind Code:

A1

Abstract:

Indazole derivatives having monocyclic amino groups represented by general formula (I), wherein R1 represents a hydrogen atom or a C1-C6 alkyl, C3-C6 alkenyl, or C3-C6 cycloalkyl group; Q represents a carbonyl, thiocarbonyl, or methylene group; and R2 is a group represented by general formula (II), (III), (IV), or (V), wherein R3 represents a C1-C6 alkyl, C3-C6 alkenyl, or benzyl group, provided that the phenyl ring of the benzyl group may be mono- or di-substituted with the same or different halogen atom or a methoxy group; m is 0 to 2; n is 2 to 3; o is 1 to 2, and p is 2 to 4. The compounds per se and pharmaceutical acceptable salts thereof have a 5-HT4 receptor agonistic activity and are useful as a medicine.

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Inventors:

SUZUKI MASASHI (JP)
UENO MASAHIRO (JP)
FUKUTOMI RYUTA (JP)
SATOH HIROAKI (JP)
KIKUCHI HARUHIKO (JP)
HAGIHARA KOICHIRO (JP)
ARAI TAKEO (JP)
TANIGUCHI SUGURE (JP)
MINO SETSUKO (JP)
NOGUCHI YUMIKO (JP)

Application Number:

PCT/JP1996/001475

Publication Date:

December 05, 1996

Filing Date:

May 31, 1996

Export Citation:

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Assignee:

NISSHIN FLOUR MILLING CO (JP)
SUZUKI MASASHI (JP)
UENO MASAHIRO (JP)
FUKUTOMI RYUTA (JP)
SATOH HIROAKI (JP)
KIKUCHI HARUHIKO (JP)
HAGIHARA KOICHIRO (JP)
ARAI TAKEO (JP)
TANIGUCHI SUGURE (JP)
MINO SETSUKO (JP)
NOGUCHI YUMIKO (JP)

International Classes:

C07D231/56; C07D401/12; (IPC1-7): C07D231/56; A61K31/445; A61K31/495; C07D401/12; C07D403/12

Foreign References:

JPH02225460A	1990-09-07
JPH02256670A	1990-10-17
JPH06135960A	1994-05-17

Other References: