Title:
INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2018/014869
Kind Code:
A1
Abstract:
The present application discloses an indole as represented by formula (I) used as a CRTH2 inhibitor, and a pharmaceutically acceptable salt or tautomer of the indole, and an application of same in treating a disease related to a CRTH2 receptor.
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Inventors:
YAO YUANSHAN (CN)
CHEN BIN (CN)
CHEN YUAN (CN)
LI AO (CN)
XU RAN (CN)
HUANG ZHENSHENG (CN)
TIAN DONGDONG (CN)
LI HONGWEI (CN)
YANG CHENGSHUAI (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
CHEN BIN (CN)
CHEN YUAN (CN)
LI AO (CN)
XU RAN (CN)
HUANG ZHENSHENG (CN)
TIAN DONGDONG (CN)
LI HONGWEI (CN)
YANG CHENGSHUAI (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2017/093860
Publication Date:
January 25, 2018
Filing Date:
July 21, 2017
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
MEDSHINE DISCOVERY INC (CN)
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D409/04; A61K31/405; A61K31/4365; A61K31/4439; A61P43/00; C07D409/06; C07D409/14; C07D495/04
Foreign References:
| CN101087784A | 2007-12-12 | |||
| CN104114169A | 2014-10-22 |
Other References:
TUMEY, L. NATHAN ET AL.: "3-Indolyl sultams as selective CRTh2 antagonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 11, 14 April 2010 (2010-04-14), pages 3287 - 3290, XP029120903
See also references of EP 3489233A4
See also references of EP 3489233A4
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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