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Title:
INDOLE AND INDOLINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/102588
Kind Code:
A3
Abstract:
The disclosure relates to indole-type piperidine compounds, indoline-type piperidine compounds and related piperidine-type bicyclic compounds containing a five-membered nitrogen- containing ring (e.g., pyrrole or dihydropyrrole) fused to a heteroaryl ring, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an indole-type piperidine compound, indoline-type piperidine compound or related piperidine-type bicycl ic compound containing a five-membered nitrogen-containing ring (e.g., pyrrole or dihydropyrrole) fused to a heteroaryl ring.

Inventors:
TAFESSE LAYKEA (US)
Application Number:
PCT/IB2013/002872
Publication Date:
September 18, 2014
Filing Date:
December 23, 2013
Export Citation:
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Assignee:
PURDUE PHARMA LP (US)
TAFESSE LAYKEA (US)
International Classes:
C07D401/14; A61K31/445; A61P25/04; C07D401/04; C07D451/04; C07D451/14; C07D471/04; C07D498/08
Domestic Patent References:
WO1996023784A11996-08-08
WO2012103806A12012-08-09
WO1998028293A11998-07-02
Foreign References:
EP1123702A12001-08-16
US20050256103A12005-11-17
EP0470039A21992-02-05
FR2767827A11999-02-26
EP0976732A12000-02-02
JP2008007416A2008-01-17
Other References:
COE J W ET AL: "Convenient Preparation of N-Substituted Indoles by Modified Leimgruber-Batcho Indole Synthesis", TETRAHEDRON LETTERS, PERGAMON, GB, vol. 37, no. 34, 19 August 1996 (1996-08-19), pages 6045 - 6048, XP004030608, ISSN: 0040-4039, DOI: 10.1016/0040-4039(96)01311-1
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