Title:
INDUCED BROWN FAT DIFFERENTIATION COMPOSITION COMPRISING ISOLIQUIRITIGENIN DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2021/182896
Kind Code:
A1
Abstract:
The present invention relates to isoliquiritigenin derivatives, and a use thereof. The isoliquiritigenin derivatives induce brown fat differentiation and do not have significant cytotoxicity. A composition, which is for inducing brown fat cells and includes the isoliquiritigenin derivatives, has the effect of reducing myocardial damage, and thus can be effectively used for preventing or treating heart disease.
Inventors:
HWANG KI CHUL (KR)
KIM SANG WOO (KR)
LEE YUN MI (KR)
CHOI JUNG WON (KR)
MOON HAN BYEOL (KR)
LIM SO YEON (KR)
LEE SEA HYOUNG (KR)
KIM SANG WOO (KR)
LEE YUN MI (KR)
CHOI JUNG WON (KR)
MOON HAN BYEOL (KR)
LIM SO YEON (KR)
LEE SEA HYOUNG (KR)
Application Number:
PCT/KR2021/003043
Publication Date:
September 16, 2021
Filing Date:
March 11, 2021
Export Citation:
Assignee:
CATHOLIC KWANDONG UNIV IND FOUND (KR)
International Classes:
A23L33/10; C07C49/303; A61K31/352; A61P9/00; C07C45/61; C07D311/32
Domestic Patent References:
| WO2013149258A2 | 2013-10-03 |
Foreign References:
| KR20160000840A | 2016-01-05 | |||
| US20070092551A1 | 2007-04-26 |
Other References:
REN BING-ZHAO; ABLISE MOURBOUL; YANG XU-CHAO; LIAO BO-ER; YANG ZHENG: "Synthesis and biological evaluation of α-methyl-chalcone for anti-cervical cancer activity", MEDICINAL CHEMISTRY RESEARCH, vol. 26, no. 9, 22 April 2017 (2017-04-22), US, pages 1871 - 1883, XP036287793, ISSN: 1054-2523, DOI: 10.1007/s00044-017-1891-0
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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