Title:
INDUCED PHASE TRANSITION METHOD FOR THE PRODUCTION OF MICROPARTICLES CONTAINING HYDROPHOBIC ACTIVE AGENTS
Document Type and Number:
WIPO Patent Application WO2002049620
Kind Code:
A3
Abstract:
Microparticles and a method for their production is described. The process of the present invention provides a simple, quick, and efficient one-pot process for the production of microparticles containing a non-water soluble active agent. The microparticles are preferably used for pharmaceutical applications and comprise at least 80 wt% microspheres.
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Inventors:
ALBAYRAK CELAL (DE)
Application Number:
PCT/US2001/050259
Publication Date:
May 15, 2003
Filing Date:
December 19, 2001
Export Citation:
Assignee:
INHALE THERAPEUTIC SYST (US)
ALBAYRAK CELAL (DE)
ALBAYRAK CELAL (DE)
International Classes:
A61K9/16; A61K9/18; A61K9/50; A61K31/337; A61K31/58; A61K47/04; A61K47/10; A61K47/18; A61K47/34; B01J13/00; B01J13/04; B01J19/00; C08L101/16; (IPC1-7): A61K9/16; A61K9/50
Domestic Patent References:
| WO1997019676A1 | 1997-06-05 | |||
| WO2000028969A2 | 2000-05-25 |
Foreign References:
| DE19916384A1 | 2000-10-05 | |||
| FR2797784A1 | 2001-03-02 |
Other References:
ALBAYRAK C ET AL: "NOVEL METHOD FOR THE PREPARATION OF DRUG LOADED NANO- AND MICROCAPSULES BY AN INDUCED PHASE TRANSITION METHOD", PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, XX, XX, 1999, pages 585 - 586, XP008007556, ISSN: 1022-0178
ALBAYRAK C: "Novel methods for the engineering of drug loaded nano- and microparticles of uniform morphology", PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, XX, XX, vol. 1, 23 June 2001 (2001-06-23), pages 846 - 847, XP002211721, ISSN: 1022-0178
ALBAYRAK C: "Novel methods for the engineering of drug loaded nano- and microparticles of uniform morphology", PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, XX, XX, vol. 1, 23 June 2001 (2001-06-23), pages 846 - 847, XP002211721, ISSN: 1022-0178
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