Title:
INDUCTIVE REGENERATION OF THE AIRWAY BY TRANSCRIPTIONAL FACTOR MODULATION OF GLANDULAR MYOEPITHELIAL STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2019/178267
Kind Code:
A3
Abstract:
Compositions and methods to modulate Lef-1/TCF/Wnt signaling ex vivo or in vivo, and assays to detect those modulators, are described.
Inventors:
ENGELHARDT JOHN (US)
LYNCH THOMAS (US)
ANDERSON PRESTON (US)
SHAHIN WEAM (US)
LYNCH THOMAS (US)
ANDERSON PRESTON (US)
SHAHIN WEAM (US)
Application Number:
PCT/US2019/022106
Publication Date:
October 10, 2019
Filing Date:
March 13, 2019
Export Citation:
Assignee:
UNIV IOWA RES FOUND (US)
ENGELHARDT JOHN F (US)
LYNCH THOMAS J (US)
ANDERSON PRESTON J (US)
SHAHIN WEAM (US)
ENGELHARDT JOHN F (US)
LYNCH THOMAS J (US)
ANDERSON PRESTON J (US)
SHAHIN WEAM (US)
International Classes:
C12N5/07; C12N5/0789
Domestic Patent References:
| WO2000038709A1 | 2000-07-06 | |||
| WO2006116503A2 | 2006-11-02 | |||
| WO2008133904A1 | 2008-11-06 | |||
| WO2008034637A1 | 2008-03-27 |
Attorney, Agent or Firm:
PERDOK, Monique, M. et al. (US)
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