Title:
INDUSTRIAL PREPARATION METHOD FOR HIGH-PURITY DICYCLOPLATIN NEEDLE-LIKE CRYSTAL
Document Type and Number:
WIPO Patent Application WO/2018/233273
Kind Code:
A1
Abstract:
Provided is an industrial preparation method for a high-purity dicycloplatin needle-like crystal, comprising: mixing and reacting carboplatin, 1,1-cyclobutane dicarboxylic acid and water, and crystallizing same to obtain a dicycloplatin needle-like crystal with a yield of more than 85% and a utilization ratio of the precious metal platinum of more than 97%. The method is green and environmentally friendly and is suitable for industrial production.
Inventors:
SONG QINHUA (CN)
FAN RULIN (CN)
FENG JIANKE (CN)
FAN RULIN (CN)
FENG JIANKE (CN)
Application Number:
PCT/CN2018/000229
Publication Date:
December 27, 2018
Filing Date:
June 20, 2018
Export Citation:
Assignee:
SONG QINHUA (CN)
FAN RULIN (CN)
FENG JIANKE (CN)
FAN RULIN (CN)
FENG JIANKE (CN)
International Classes:
C07F15/00; A61K31/282; A61P31/04; A61P31/12
Foreign References:
CN106132408A | 2016-11-16 | |||
CN104693245A | 2015-06-10 | |||
CN1311183A | 2001-09-05 | |||
CN104127402A | 2014-11-05 |
Attorney, Agent or Firm:
SONG, Qinhua (CN)
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