Title:
INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION
Document Type and Number:
WIPO Patent Application WO2001092253
Kind Code:
A3
Abstract:
The present invention relates to small molecules according to formula (I) that are potent inhibitors of alpha L beta 2 mediated cell adhesion and which could be useful for the treatment of inflammatory diseases:
Inventors:
SIRCAR ILA (US)
XIE YUN FENG (US)
SMITH NICHOLAS (US)
FURTH PAUL S (US)
XIE YUN FENG (US)
SMITH NICHOLAS (US)
FURTH PAUL S (US)
Application Number:
PCT/US2001/012323
Publication Date:
May 23, 2002
Filing Date:
April 17, 2001
Export Citation:
Assignee:
TANABE SEIYAKU CO (JP)
SIRCAR ILA (US)
XIE YUN FENG (US)
SMITH NICHOLAS (US)
FURTH PAUL S (US)
SIRCAR ILA (US)
XIE YUN FENG (US)
SMITH NICHOLAS (US)
FURTH PAUL S (US)
International Classes:
A61K31/4439; A61P1/00; A61P1/04; A61P3/10; A61P7/02; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P37/00; A61P37/08; C07D401/04; (IPC1-7): C07D401/04; A61K31/4166; A61P29/00
Domestic Patent References:
| WO2001007048A1 | 2001-02-01 |
Foreign References:
| EP0770613A1 | 1997-05-02 |
Other References:
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KELLY, TERENCE A. ET AL: "Cutting edge: a small molecule antagonist of LFA-1-mediated cell adhesion", XP002186964, retrieved from STN Database accession no. 132:58885
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