Title:
INHIBITORS OF HIF AND ANGIOGENESIS
Document Type and Number:
WIPO Patent Application WO/2011/133659
Kind Code:
A3
Abstract:
Inhibitors of the Hypoxia Inducible Factor (HIF) and angiogenesis and their methods of use including the treatment of cancer, hypoxia related pathologies, disorders leading to ischemia, for example stroke and ischemic heart disease, and non-cancerous angiogenic diseases are provided.
More Like This:
| WO/2005/037815 | A MANUFACTURING PROCESS OF ISOFLAVAN OR ISOFLAVENE DERIVATIVES |
| WO/2009/158426 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES |
| WO/1993/010741 | SEX STEROID ACTIVITY INHIBITORS |
Inventors:
VAN MEIR ERWIN (US)
WANG BINGHE (US)
WANG BINGHE (US)
Application Number:
PCT/US2011/033230
Publication Date:
March 15, 2012
Filing Date:
April 20, 2011
Export Citation:
Assignee:
UNIV EMORY (US)
UNIV GEORGIA STATE RES FOUND (US)
VAN MEIR ERWIN (US)
WANG BINGHE (US)
UNIV GEORGIA STATE RES FOUND (US)
VAN MEIR ERWIN (US)
WANG BINGHE (US)
International Classes:
C07D311/04; A61K31/352; A61K31/47; A61P35/00; C07D215/12; C07D307/81; C07D405/12; C07D491/052
Domestic Patent References:
| WO2010039977A2 | 2010-04-08 | |||
| WO2008136756A1 | 2008-11-13 | |||
| WO2008113006A1 | 2008-09-18 | |||
| WO2007136592A2 | 2007-11-29 |
Other References:
RAMBABU GUNDLA ET AL.: "Discovery of Novel Small-Molecule Inhibitors of Human Epidermal Growth Factor Receptor-2: Combined Ligand and Target-Based Approach", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 12, 2008, pages 3367 - 3377
Attorney, Agent or Firm:
MASON, James, C. et al. (Office of Technology Transfer1599 Ciifton Road NE, 4th Floo, Atlanta GA, US)
Download PDF: