INHIBITORY MATERIAL AGAINST HUMAN BODY-DERIVED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE-DEPENDENT STEROID DEHYDROGENASE-LIKE, AND ANTICANCER AGENT COMPRISING SAME AS EFFECTIVE INGREDIENT OR PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR TREATMENT OF HYPERLIPIDEMIA

WIPO Patent Application WO/2020/046020

A1

A nicotinamide adenine dinucleotide phosphate-dependent steroid dehydrogenase-like (NSDHL) inhibitor provided according to an aspect of the present invention can be used not only as an anticancer agent capable of overcoming resistance to EGFR-targeting anticancer agents, but also advantageously in the treatment of hyperlipidemia.

JP3179515	[Title of Invention] Method for producing 2-chlorothiazoles
JP5570503	The sulfoxy imine amide compound for animal noxious organism extermination

LEE BONG-JIN (KR)
LEE KYU-YEON (KR)
LEE SANG JAE (KR)
KIM DONG-GYUN (KR)
LEE JOO YOUN (KR)
JEONG KWAN-YOUNG (KR)
YANG HEUI CHERL (KR)
LEE HYEON-KYU (KR)
KIM HYOUN SOOK (KR)

PCT/KR2019/011094

March 05, 2020

August 29, 2019

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SEOUL NAT UNIV R&DB FOUNDATION (KR)
KOREA RES INST CHEMICAL TECH (KR)
NAT CANCER CT (KR)

C07D277/32; A61K31/426; A61P3/06; A61P35/00

WO2011135303A2	2011-11-03
WO1994029287A1	1994-12-22
WO2017215552A1	2017-12-21

US20100016292A1

2010-01-21

JOHNSON, S. L.: "Rhodanine derivatives as selective protease inhibitors against bacterial toxins", CHEMICAL BIOLOGY & DRUG DESIGN, vol. 71, no. 2, 2008, pages 131 - 139, XP055697212
SUN, L.: "Discovery of 1, 3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 29, no. 10, 2019, pages 1187 - 1193, XP055697214

LEE, Won Hee (KR)

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