Title:
THE INHIBITORY MELANOGENESIS BY COFFEE OIL EXTRACTED BY SUPERCRITICAL CO2
Document Type and Number:
WIPO Patent Application WO/2014/069677
Kind Code:
A1
Abstract:
The coffee oil extracted by supercritical carbon dioxide is useful for skin whitening by inhibition of melanogenesis. A effective dosage of coffee oil wherein said dosage of 10 mg/L of treating oil, the total melanin content was decreased over 25%. The coffee oil inhibits the early period of melanogenesis is which was proved by the down-regulation of 8 identified proteins including -MSH, MC1R, ACTHR, MITF, PKC-, SCF, TYR and TRP-2.
Inventors:
BYUN SANGYO (KR)
SONG YOUNGKEUN (KR)
SONG YOUNGKEUN (KR)
Application Number:
PCT/KR2012/008909
Publication Date:
May 08, 2014
Filing Date:
October 29, 2012
Export Citation:
Assignee:
AJOU UNIV IND ACAD COOP FOUND (KR)
International Classes:
A61K36/74; A61K8/97; A61P17/00; A61Q19/02
Domestic Patent References:
| WO2012013764A2 | 2012-02-02 |
Foreign References:
| US20060018986A1 | 2006-01-26 | |||
| KR20110077722A | 2011-07-07 | |||
| KR20070015569A | 2007-02-05 |
Other References:
LEE, J. H.: "Studies on Enhancement of Coffee Flavors and Efficacy by Supercritical Carbon Dioxide", THESIS OF GRADUATE SCHOOL OF AJOU UNIVERSITY, 2008, pages 1, 4, 7, 9, 10, 35 - 46
PARK, K. S.: "The Study of Cosmeceutical Activities from Coffee Beans and Application of MLV Liposomes on Advanced Formulation", THESIS OF GRADUATE SCHOOL OF DAEGU HAANNY UNIVERSITY, 2010, pages 47 - 58
PARK, K. S.: "The Study of Cosmeceutical Activities from Coffee Beans and Application of MLV Liposomes on Advanced Formulation", THESIS OF GRADUATE SCHOOL OF DAEGU HAANNY UNIVERSITY, 2010, pages 47 - 58
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (innoplex 1-cha 151, Gasan digital 1-ro,Geumcheon-gu, Seoul 153-803, KR)
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