INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION

Title:

INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION

Document Type and Number:

WIPO Patent Application WO/2010/136594

Kind Code:

A3

Abstract:

The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation.

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Inventors:

BERTHOLON ISABELLE (FR)
BRUNEL FLORENCE (FR)
HERBAGE BENJAMIN (FR)
VILLARD CHRISTOPHE (FR)

Application Number:

PCT/EP2010/057493

Publication Date:

December 22, 2011

Filing Date:

May 28, 2010

Export Citation:

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Assignee:

SYMATESE (FR)
GALDERMA RES & DEV (FR)
BERTHOLON ISABELLE (FR)
BRUNEL FLORENCE (FR)
HERBAGE BENJAMIN (FR)
VILLARD CHRISTOPHE (FR)

International Classes:

A61K31/498; A61K9/00; A61K31/728; A61K38/48; A61K47/26

Domestic Patent References:

WO2009065116A1	2009-05-22
WO2009017705A1	2009-02-05
WO2006092619A1	2006-09-08
WO2007056233A1	2007-05-18
WO2009101210A1	2009-08-20
WO2009082452A1	2009-07-02

Foreign References:

US20080293728A1	2008-11-27
EP2036538A1	2009-03-18

Other References:

KLEIN J A: "Tumescent Technique for Regional Anesthesia Permits Lidocaine Doses of 35 mg/kg for Liposuction", THE JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, ELSEVIER SCIENCE INC, vol. 16, 1 March 1990 (1990-03-01), pages 248 - 263, XP009149012, ISSN: 0148-0812
NAOUM C ET AL: "DERMAL FILLER MATERIALS AND BOTULIN TOXIN", INTERNATIONAL JOURNAL OF DERMATOLOGY, WILEY-BLACKWELL PUBLISHING LTD, UK, vol. 40, no. 10, 1 October 2001 (2001-10-01), pages 609 - 621, XP009085797, ISSN: 0011-9059, DOI: 10.1046/J.1365-4362.2001.01111.X
See also references of EP 2435045A2

Attorney, Agent or Firm:

BUCHET, Anne et al. (Le Contemporain50 Chemin de la Bruyère, Dardilly Cédex, FR)

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