Title:
INJECTABLE FOAM AND NOVEL PHARMACEUTICAL APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2003/013475
Kind Code:
A1
Abstract:
The invention relates to novel pharmaceutical applications of injectable foam. The provision of a medicament, intended for parenteral administration, on bubbles formed with sterile gases produces an exponential increase in the active surface area of the bubble as the diameter of said bubble decreases; alters the distribution kinetics of same; and, by means of micronisation, increases the therapeutic effect thereof. Moreover, the echogenicity of the bubbles allows them to be monitored echographically once they have been injected, thereby enabling the medicament to be viewed. In addition, the manoeuvrability of said medicament enables it to be directed to the selected location or prevented from reaching undesirable areas. Said galenic form of foam is suitable for the treatment of pathologies for which greater local action from the injected medicaments is required which cannot be achieved with the pharmaceutical forms currently used.
Inventors:
GARCIA-OLMEDO DOMINGUEZ MARIA (ES)
Application Number:
PCT/ES2001/000317
Publication Date:
February 20, 2003
Filing Date:
August 08, 2001
Export Citation:
Assignee:
GARCIA-OLMEDO DOMINGUEZ MARIA (ES)
International Classes:
A61K9/12; A61K31/505; A61K31/5575; A61K31/56; A61K45/00; A61P1/16; A61P5/00; A61P5/38; A61P9/10; A61P13/12; A61P23/00; A61P29/00; A61P31/00; A61P31/10; A61P31/12; A61P35/00; A61P43/00; (IPC1-7): A61K9/12
Domestic Patent References:
| WO1992005806A1 | 1992-04-16 |
Foreign References:
| EP0656203A1 | 1995-06-07 | |||
| US4466442A | 1984-08-21 | |||
| EP0324938A1 | 1989-07-26 |
Other References:
MONFREUX, A.: "Traitement sclérosant des troncs saphéniens et leurs collatérales de gros calibre par la méthode MUS", PHLEBOLOGIE, vol. 50, no. 3, 1997, pages 351 - 353, XP002195121
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