Title:
INJECTABLE MAGNESIUM OXYCHLORIDE CEMENT FOAM (MOCF) -DERIVED SCAFFOLD FOR TREATING OSTEOPOROTIC BONE DEFECTS
Document Type and Number:
WIPO Patent Application WO/2024/067485
Kind Code:
A1
Abstract:
Provided herein are magnesium oxychloride cement compositions having a micro-/macro-two-tier porous structure derived from a Pickering foam form of the compositions. The compositions include magnesium oxide, magnesium chloride, water, and one or more surface modifying agents that modify at least a portion of the magnesium oxide, thereby creating particulates sufficient for stabilizing the Pickering foam. Also provided are bone repair scaffolds, and methods for producing the provided compositions and scaffolds and using them to repair bone defects.
Inventors:
NGAI TO (CN)
ZHU YUWEI (CN)
QIN LING (CN)
XU JIANKUN (CN)
ZHU YUWEI (CN)
QIN LING (CN)
XU JIANKUN (CN)
Application Number:
PCT/CN2023/121109
Publication Date:
April 04, 2024
Filing Date:
September 25, 2023
Export Citation:
Assignee:
UNIV HONG KONG CHINESE (CN)
International Classes:
C04B28/32; A61L27/56; A61L31/12
Domestic Patent References:
| WO2008117043A2 | 2008-10-02 |
Foreign References:
| CN111840652A | 2020-10-30 | |||
| US3969453A | 1976-07-13 | |||
| CN114601969A | 2022-06-10 | |||
| CN111888521A | 2020-11-06 | |||
| CN104591679A | 2015-05-06 |
Other References:
ZHU YUWEI, GUO JIAXIN, SHENG YIFENG, XU JIANKUN, QIN LING, NGAI TO: "Injectable magnesium oxychloride cement foam-derived scaffold for augmenting osteoporotic defect repair", JOURNAL OF COLLOID AND INTERFACE SCIENCE, ACADEMIC PRESS,INC., US, vol. 640, 1 June 2023 (2023-06-01), US , pages 199 - 210, XP093151544, ISSN: 0021-9797, DOI: 10.1016/j.jcis.2023.02.109
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LTD. (CN)
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