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Title:
INJECTION COMPRISING DOCETAXEL AND ITS PREPARATION
Document Type and Number:
WIPO Patent Application WO/2009/079878
Kind Code:
A1
Abstract:
The invention provides an injection comprising docetaxel, which contains a mother liquid, ethanol for preventing gel formation of injection, water for keeping the mother liquid in a uniformly flowing state. The mother liquid is a solution containing docetaxel and one or more pharmaceutically acceptable surfactants. The invention also provides a process for preparing the injection consisting of mixing the mother liquid with ethanol, then adding water and mixing uniformly. The injection has high uniformity and high stability, and can extend the time needed to form a crystal precipitation of docetaxel in the injectable solution.

Inventors:
HU YUFANG (CN)
LIN CHUNCHOU (CN)
HUANG YAOKUN (CN)
HUANG SHOUMIN (CN)
Application Number:
PCT/CN2007/071274
Publication Date:
July 02, 2009
Filing Date:
December 19, 2007
Export Citation:
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Assignee:
TTY BIOPHARM CO LTD (CN)
HU YUFANG (CN)
LIN CHUNCHOU (CN)
HUANG YAOKUN (CN)
HUANG SHOUMIN (CN)
International Classes:
A61K31/337; A61K9/08; A61P35/00
Domestic Patent References:
WO2007124700A22007-11-08
Foreign References:
US5750561A1998-05-12
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (Block A Corporate Square,No. 35 Jinrong Street, Beijing 2, CN)
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