[0001] Injector Usable With Different Dimension Cartridges

CROSS-REFERENCE TO RELATED APPLICATIONS

[0002] This application claims priority from U.S. Provisional Patent Application No.

62/609,740, titled“Adapter To Guide Cartridge With Integrated Shield To Protect Septum Puncture Needle From Finger Stick Hazard,” filed on December 22, 2017, the entire contents of which are incorporated by reference herein.

BACKGROUND OF THE DISCLOSURE

[0003] The present disclosure is generally directed to a cartridge loaded injector, and, more particularly, to an injector compatible for use with cartridges of differing dimensions.

[0004] An injector, such as, for example, a drug injector, is typically loaded with a cartridge containing therein a substance to be dispensed. The cartridge may be pre-loaded prior to delivery to a user, or, alternatively, the cartridge may be loaded by the user prior to use. Drug cartridges are manufactured and sold in different sizes and dimensions. Moreover, even cartridges manufactured via the same processes are subject to variations in dimensions, i.e., manufacturing tolerance. One or more of the manufacturing process and the material used to form the cartridges contributes to manufacturing tolerance. For example, glass cartridges are generally formed having lower precision, and, therefore, have greater variation among cartridges than cartridges formed from molded polymer(s) which are generally formed having greater precisions and lower variation among cartridges. Nevertheless, in the pharmaceutical industry, for example, glass cartridges remain more prevalent.

[0005] One drawback of conventional injectors is that they are generally manufactured to operate with a particular corresponding cartridge. Moreover, lower precision cartridges intended to work with a particular injector may nevertheless fail to be usable with the injector if formed exhibiting too large a variation from the intended dimensions.

[0006] Therefore, it would be advantageous to manufacture an injector configured to be usable with multiple differently dimensioned cartridges and cartridges subject to larger manufacturing tolerances. BRIEF SUMMARY OF THE DISCLOSURE

[0007] Briefly stated, one aspect of the present disclosure is directed to an injector including a body, and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body is sized for independently receiving either of a first cartridge or a radially differently dimensioned second cartridge therein. The pathway includes a proximal opening for receiving the first cartridge or the second cartridge therethrough and a coupler mounted at a distal end of the pathway and engageable with the first cartridge or the second cartridge for fluidly connecting the first cartridge or the second cartridge with the injection needle. At least two adapter collars are mounted within the pathway. A first adapter collar of the at least two adapter collars is configured to receive one of the first cartridge or the second cartridge therethrough upon insertion of the first cartridge or the second cartridge into the pathway, and configured to engage a portion of the first cartridge to stabilize the first cartridge within the pathway. A second adapter collar of the at least two adapter collars is configured to receive either of the first cartridge or the second cartridge therethrough upon insertion of the first cartridge or the second cartridge into the pathway, and configured to engage a portion of the second cartridge to stabilize the second cartridge within the pathway.

[0008] Another aspect of the present disclosure is directed to an injector including a body and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body for receiving a cartridge includes a proximal opening for receiving the cartridge therethrough and a coupler mounted at a distal end of the pathway and engageable with the cartridge for fluidly connecting the cartridge with the injection needle. An adapter collar is mounted within the pathway and configured to receive the cartridge therethrough upon insertion of the cartridge into the pathway and is configured to engage a portion of the cartridge to stabilize the cartridge within the pathway. The adapter collar includes a disk and a plurality of angularly spaced apart cantilevered fingers projecting from the disk. The fingers are oriented in an unbiased, radially inwardly projecting closed position covering the coupler, and the fingers are deflectable distally and radially outwardly relative to one another by the cartridge into an open position exposing the coupler upon advancement of the cartridge through the disk.

[0009] Another aspect of the present disclosure is directed to an injector device kit including an injector and a plurality of adapter collars. The injector includes a body and an injection needle movably mounted to the body. The injection needle is displaceable between a retracted position and an injection position. A pathway within the body is sized for independently receiving any one of multiple radially differently dimensioned cartridges. The pathway includes a proximal opening for receiving the cartridge therethrough and a cartridge piercing needle mounted at a distal end of the pathway and projecting into the pathway, the cartridge piercing needle being in fluid communication with the injection needle and engageable with the cartridge for fluidly connecting the cartridge with the injection needle. The plurality of adapter collars are each removably mountable within the pathway, each adapter collar being configured to receive a corresponding one of the multiple radially differently dimensioned cartridges therethrough and engage a portion of the cartridge to stabilize the cartridge within the pathway and substantially co-axially align the cartridge with the cartridge piercing needle. Mounting of a respective adapter collar within the pathway enables usage of the injector with the respective corresponding cartridge.

BRIEF DESCRIPTION OF THE DRAWINGS

[0010] The following detailed description of aspects of the disclosure will be better understood when read in conjunction with the appended drawings. It should be understood, however, that the invention is not limited to the precise arrangements and instrumentalities shown. In the drawings:

[0011] Fig. 1 is a top and front perspective view of a wearable injector, in accordance with an embodiment of the present disclosure;

[0012] Fig. 2 is a cross-sectional view of the injector of Fig. 1, taken along the sectional line 2-2 of Fig. 1, with an activation button assembly in an unactuated position thereof and an injection needle in a retracted position thereof;

[0013] Fig. 3 is a cross-sectional view of the injector of Fig. 1, taken along the sectional line 2-2 of Fig. 1, with the activation button assembly in an actuated position thereof and the injection needle in an injection position thereof;

[0014] Fig. 4A is a partial cross-sectional view of the injector of Fig. 1, taken along the sectional line 4-4 of Fig. 1, the injector having an adapter collar mounted therein with cantilevered fingers thereof in a closed position;

[0015] Fig. 4B is an enlarged, partial view of Fig. 4A;

[0016] Fig. 5 is an enlarged, partial view of Fig. 4A with the cantilevered fingers of the adapter collar in an open position and the cartridge pierced by a cartridge piercing needle of the injector;

[0017] Fig. 6A is a perspective view of a first configuration of an adapter collar of the invention with the cantilevered fingers thereof in the closed position;

[0018] Fig. 6B is a perspective view of the adapter collar of Fig. 6A, with the cantilevered fingers thereof in the open position; [0019] Fig. 7A is a perspective view of a second configuration of an adapter collar of the invention with the cantilevered fingers thereof in the closed position and an intact frangible ring connecting the cantilevered fingers;

[0020] Fig. 7B is a perspective view of the adapter collar of Fig. 7A, with the cantilevered fingers thereof in the open position, fracturing the frangible ring;

[0021] Fig. 8A is a schematic illustration of a cartridge door of the injector of Fig. 1, having a cartridge inserted therein stabilized by a proximal adapter collar of two adapter collars mounted within an interior pathway of the cartridge door;

[0022] Fig. 8B is a schematic illustration of the cartridge door of the injector of Fig. 1, having a radially differently dimensioned cartridge inserted therein stabilized by a distal adapter collar of the two adapter collars mounted within the interior pathway;

[0023] Fig. 9A is a schematic illustration of the cartridge door of the injector of Fig. 1, having a cartridge inserted therein stabilized by the interior pathway; and

[0024] Fig. 9B is a schematic illustration of the cartridge door of the injector of Fig. 1, having a radially differently dimensioned cartridge inserted therein stabilized by an adapter collar mounted within the interior pathway.

DETAILED DESCRIPTION OF THE DISCLOSURE

[0025] Certain terminology is used in the following description for convenience only and is not limiting. For example, the words“lower,”“bottom,”“upper” and“top” designate directions in the drawings to which reference is made. The words“inwardly,” “outwardly,” “upwardly” and “downwardly” refer to directions toward and away from, respectively, the geometric center of the injector, and designated parts thereof, in accordance with the present disclosure. Unless specifically set forth herein, the terms“a,”“an” and“the” are not limited to one element, but instead should be read as meaning“at least one.” The terminology includes the words noted above, derivatives thereof and words of similar import.

[0026] It should also be understood that the terms“about,” “approximately,” “generally,” “substantially” and like terms, used herein when referring to a dimension or characteristic of a component of the invention, indicate that the described dimension/characteristic is not a strict boundary or parameter and does not exclude minor variations therefrom that are functionally similar. At a minimum, such references that include a numerical parameter would include variations that, using mathematical and industrial principles accepted in the art (e.g., rounding, measurement or other systematic errors, manufacturing tolerances, etc.), would not vary the least significant digit. [0027] Referring to the drawings in detail, wherein like numerals indicate like elements throughout, there is shown in Figs. 1-9B an injector, generally designated 10, in accordance with an embodiment of the present disclosure. In the illustrated embodiment, the injector 10 takes the form of a wearable injector (patch injector), such as, for example, without limitation, a wearable drug injector, but the disclosure is not so limited. As should be understood by those of ordinary skill in the art, the injector 10 generally includes a body 11. The body 11 includes a main housing 12 having a first surface 14 configured to contact a skin surface of a user (not shown), e.g., a patient, the first surface 14 having an opening l4a therein. In the illustrated embodiment, the first surface 14 defines a base surface of the injector main housing 12, but the disclosure is not so limited. The main housing 12 also includes a second surface 16 opposing the first surface 14. In the illustrated embodiment, the second surface 16 defines a top, external surface of the injector main housing 12, but the disclosure is not so limited.

[0028] As shown in Figs. 2-3, a needle hub 18, constructed, for example, from a polymeric or metal material, combinations thereof, or the like, is movably mounted within the main housing 12 of the injector body 11 and an injection needle 20 is supported by the movable needle hub 18 in a manner well understood by those of ordinary skill in the art. In the illustrated embodiment, the needle hub 18 and the injection needle 20 are axially translatable (or otherwise displaceable) in the direction of axis A (Fig. 2) extending substantially perpendicularly to the first surface 14, between a retracted position (Fig. 2), wherein at least a tip 20a of the injection needle 20 is contained within the injector main housing 12, and an injection position (Fig. 3), wherein at least the tip 20a of the injection needle 20 protrudes from the injector main housing 12 through the opening l4a. As should be understood by those of ordinary skill in the art, however, the axis A may be positioned at angles other than 90° relative to the first surface 14. As also should be understood, the injection needle 20 may be movably mounted within the injector main housing 12 via mechanisms other than the needle hub 18.

[0029] In some embodiments, a depressible activation button assembly 22, constructed, for example, from a polymeric or metal material, combinations thereof, or the like, may be movably mounted to the injector main housing 12 and operatively connected to the injection needle 20. The activation button assembly 22 may be translatable, i.e., depressible, along a button axis B (Fig. 2) from an unactuated position (Figs. 1, 2) to an actuated position (Fig. 3) in a manner well understood by those of ordinary skill in the art, to activate the injector 10. In one embodiment, the button axis B may be parallel to the axis A, but the disclosure is not so limited. Activation of the injector 10 includes, for example, driving the injection needle 20 from the retraction position to the injection position thereof to perform an injection.

[0030] A biasing member 24 may be operatively connected with the activation button assembly 22 and the injection needle 20 (Figs. 2, 3), but the disclosure is not so limited. As one alternative example, the biasing member 24 may be connected with the second surface 16 and the injection needle 20. The biasing member 24 is stabilized in a stored energy state in the unactuated position of the activation button assembly 22 (Fig. 2) and released into an energy releasing state, when the activation button assembly 22 is translated into the actuated position thereof (Fig. 3), to drive the injection needle 20 along the direction of axis A from the retracted position thereof to the injection position thereof. As should be understood by those of ordinary skill in the art, the stored energy state of the biasing member 24 is a state in which the biasing member 24 stores at least some potential energy. The energy releasing state of the biasing member 24 is a state of the biasing member 24 in which the biasing member 24 releases at least some of the previously stored potential energy from the stored energy state.

[0031] In one embodiment, the biasing member 24 may take the form of a coil spring mounted between the needle hub 18 and the activation button assembly 22, i.e., the spring 24 abuts the activation button assembly 22 at one end and abuts the needle hub 18 at an opposing end. In the energy storing state, the coil spring 24 is at least partially compressed. In the energy releasing state, the coil spring 24 expands (relative to the at least partially compressed energy storing state) to drive the needle hub 18 and the injection needle 20 into the injection position thereof. As should be understood by those of ordinary skill in the art, however, the biasing member 24 may alternatively take the form of other members capable of storing and releasing energy. Non-limiting examples include other springs (e.g., torsion or leaf springs), elastic bands, and the like. Alternatively, the biasing member 24 may take the form of an electromechanical or pneumatic actuator configured to apply a translational force onto the injection needle 20 when the activation button assembly 22 is depressed into the actuated position thereof.

[0032] The injector body 11 further includes a cartridge door 26 movably, e.g., pivotably, mounted to the injector main housing 12, between an open position (not shown) and a closed position (Fig. 1). As shown in Fig. 4A, the cartridge door 26 includes a proximal open end 26a and an interior pathway 26b for receiving (in the open position of the door) one of a plurality of differently dimensioned cartridges 28 therein, e.g., at least a first cartridge 28' or a differently dimensioned second cartridge 28" e.g., radially different, (as will be described in further detail below, see, e.g., Figs. 8A-9B). As should be understood, a cartridge 28 usable with the injector 10 includes a reservoir 28a containing a substance (not shown), e.g., medicament, to be dispensed from the injector 10 through the injection needle 20, and having a first, distal opening sealed by a pierceable septum 29 in a manner well understood by those of ordinary skill in the art.

[0033] The cartridge door 26 further includes a coupler 26c mounted within the interior pathway 26b. In the illustrated embodiment, the coupler 26c takes the form of a cartridge piercing needle 26c, but the disclosure is not so limited. As shown schematically in Figs. 8A-9B, the cartridge piercing needle 26c is fluidly connected to the injection needle 20 in a manner well understood by those of ordinary skill in the art, e.g., via a flexible tube (partially shown in Figs. 4B, 5) extending from the piercing needle 26c to the injection needle 20. In the illustrated embodiment, the cartridge piercing needle 26c is positioned proximate a closed, distal end of the interior pathway 26b, opposite the proximal open end 26a (Figs. 4A, 8A-9B). The cartridge piercing needle 26c extends inwardly into the interior pathway 26b and terminates at a tip of the needle 26c, positioned to face and align with the pierceable septum 29 of the cartridge 28 when the cartridge 28 is inserted into the cartridge door 26. The cartridge piercing needle 26c is configured to fully penetrate the pierceable septum 29 of the cartridge 28 to fluidly connect the substance within the cartridge 28 with the injection needle 20 when the cartridge 28 is sufficiently inserted into the interior pathway 26b and/or when the injector 10 is activated.

[0034] As shown in Figs. 4-5, at least one adapter collar 30, 30' is mountable within the interior pathway 26b (in an orientation generally transverse to the cartridge insertion path). The adapter collar 30, 30' is configured, i.e., sized and dimensioned, to receive any cartridge 28 usable with the injector 10 therethrough upon insertion of the cartridge 28 into the interior pathway 26b, and configured to engage a portion of a particularly dimensioned corresponding cartridge 28 to stabilize the cartridge 28 within the interior pathway 26b.

[0035] In one configuration, as shown best in Figs. 6A-6B, the adapter collar 30 includes a disk 32 and a plurality of angularly spaced ribs 34 projecting radially inwardly into the interior pathway 26b from the disk 32. In the illustrated embodiment, the adapter collar 30 includes three ribs 34 generally equally angularly spaced apart about the interior of the disk 32, but the disclosure is not so limited. The ribs 34 are substantially equally sized, dimensioned and configured to engage and stabilize the corresponding cartridge 28 in a position aligned, e.g., substantially co-axially, with the cartridge piercing needle 26c.

[0036] In one configuration, as shown in Figs. 6A-6B, one or more of the ribs 34 each includes a first segment 34a projecting primarily radially inwardly from the disk 32, a second segment 34b projecting primarily distally (i.e., toward the cartridge piercing needle 26c) from the first segment 34a and a third segment 34c projecting primarily radially inwardly from the second segment 34b. The first and third segments 34a and 34c may also be slightly angled distally and/or be distally flexible upon engagement of the ribs 34 with a cartridge 28 to better align the cartridge 28 with the cartridge piercing needle 26c. As should be understood by those of ordinary skill in the art, however, the ribs 34 may be employed in alternative configurations capable of performing the function of the ribs 34 described herein.

[0037] In some embodiments, the adapter collar 30 may also include a plurality of angularly spaced apart cantilevered fingers 36 projecting from the disk 32. In the illustrated embodiment, the adapter collar 30 includes three fingers 36 generally equally angularly spaced apart about the interior of the disk 32, but the disclosure is not so limited. As shown in Figs. 4A, 4B and 6A, the fingers 36 are oriented in a radially inwardly projecting, closed position when unbiased by a cartridge 28, i.e., when a cartridge 28 has not been advanced past the fingers 36. The fingers 36 are dimensioned, such that the fingers 36 cover the cartridge piercing needle 26c when in the closed position. For example, the fingers 36 may extend radially inwardly proximate to the central axis of the disk 32. Thus, in the closed position thereof, the fingers 36 assist in preventing contact between the cartridge piercing needle 26c and a user’s hands/fmgers (or other of a user’s body parts), and, therefore, assist in preventing needle stick injuries.

[0038] As shown in Figs. 5 and 6B, the cantilevered fingers 36 are deflectable distally and radially outwardly (generally at the interface between the finger 36 and the disk 32) relative to one another into an open position exposing the cartridge piercing needle 26c, upon advancement of a cartridge 28 beyond the disk 32. That is, the cartridge 28 deflects the fingers 36 into the open position thereof upon advancement of the cartridge 28 beyond the position of the fingers 36 in the closed position thereof, exposing the cartridge piercing needle 26c to penetrate the septum 29 of the cartridge 28.

[0039] In one configuration, as shown in Figs. 6A-6B, one or more of the fingers 36 each include a first segment 36a projecting primarily radially inwardly from the disk 32. The interface between the first segment 36a and the disk 32 may define, for example, a living hinge having a natural bias to orient in the closed position in the absence of an external force by a cartridge 28. A second segment 36b projects primarily distally from the first segment 36a and a third segment 36c projects primarily radially inwardly from the second segment 36b. A fourth segment 36d may project further radially inwardly and also project proximally from the third segment 36c to provide additional vertical clearance above the cartridge piercing needle 26c. One or more of the segments 36a-36d may also define living hinges at the respective interfaces therebetween to provide additional flexibility to the fingers 36. As should be understood, the lengths of the segments 36a-d behave as moment arms for the deflection of the fingers 36. Accordingly, the lengths of the segments 36a-d may be configured to generally set the advancement force required by a cartridge 28 to deflect the fingers 36 from the closed position to the open position thereof. As also should be understood by those of ordinary skill in the art, the fingers 36 may be employed in alternative configurations capable of performing the function of the fingers 36 described herein.

[0040] Figs. 7A-7B illustrate an alternative configuration of the adapter collar 30'. This configuration is similar to that of the configuration of Figs. 6A-6B, and, therefore, the description of certain similarities between the configurations of Figs. 7A-7B and Figs. 6A-6B may be omitted herein for the sake of brevity and convenience, and, therefore, is not limiting.

[0041] One difference of the adapter collar 30' over the adapter collar 30 (as shown in the figures) is the addition of a frangible, i.e., intentionally breakable, member 38 connecting the cantilevered fingers 36' to one another in the closed position thereof. In the illustrated embodiment, the frangible member 38 takes the form of a frangible ring, but the disclosure is not so limited. As shown best in Fig. 7A, the frangible ring 38 includes at least one scored segment 38a, e.g., a scored segment 38a between each cantilevered finger 36', defining the intentionally breakable segment(s) of the ring 38 (Fig. 7B). As should be understood by those of ordinary skill in the art, the scored segments 38a of the frangible ring 38 define a pre-set breaking force of the frangible ring 38, which must be exceeded to separate and disconnect the ring 38 in order to separate and disconnect the fingers 36' from one another and deflect the fingers 36' from the closed position to the open position thereof. As should be understood, the fingers 36 of the adapter collar 30 may also be joined by frangible members similar to the frangible member 38 joining the fingers 36' of the adapter collar 30'.

[0042] In one configuration of the adapter collar 30', one or more of ribs 34' takes the form of a generally arcuate member extending radially inwardly and distally from the disk 32, having a convex surface thereof facing toward the central axis of the disk 32, but the disclosure is not so limited. Additionally, or alternatively, one or more of the cantilevered fingers 36' defines a generally S-shaped curvilinear contour, extending radially inwardly and distally from the disk 32 (assisting in cartridge 28 lead in), but the disclosure is not so limited.

[0043] As shown best in Figs. 4A-5, at least one adapter collar 30, 30' is mounted within the interior pathway 26b. In one configuration, the adapter collar 30, 30' may be removably mounted within the interior pathway 26b (intentionally removable without damaging the collar 30, 30' and/or the interior pathway 26b). For example, the interior pathway 26b may include a radially inwardly extending annular lip 40 projecting from the sidewall of the interior pathway 26b, or radially inwardly extending lip segments 40 projecting from the sidewall of the interior pathway 26b angularly spaced (in substantially the same plane) about the sidewall, upon which the adapter collar 30, 30' may be supported. Alternatively, or additionally, the adapter collar 30, 30' may be mounted within the interior pathway 26b via a friction fit with the sidewall of the interior pathway 26b. In one embodiment, the adapter collar 30, 30' may include mounting slot 32a in the disk 32 thereof, for receiving the annular lip segments 40. As should be understood by one those of ordinary skill in the art, however, the adapter collar 30, 30' may be removably mounted within the interior pathway 26b via any of numerous mounting means currently known, or that later become known. Alternatively, an adapter collar 30, 30' may be permanently (i.e., non-removable without damaging the collar 30, 30' and/or the interior pathway 26b) mounted within the interior pathway 26b or integrally formed with the interior pathway 26b. For injectors 10 having more than one adapter collar 30, 30' mounted within the interior pathway 26b thereof (as will be discussed in further detail below), the adapter collars 30, 30', may be integrally, permanently or removably mounted therein, or any combination thereof.

[0044] In use, an injector 10 includes at least one adapter collar 30, 30' mounted within the interior pathway 26b, corresponding to a cartridge 28 intended for use with the injector 10 (Figs. 4A, 4B). The cartridge 28 is inserted into the interior pathway 26b via the proximal open end 26a thereof and advanced through the adapter collar 30, 30' and into engagement with the cartridge piercing needle 26c (Fig. 5), i.e., piercing the septum 29. The adapter collar 30, 30' is configured (via the size and dimension of the ribs 34, 34') to engage a portion of the corresponding cartridge 28 to stabilize the cartridge 28 within the interior pathway 26b and align, e.g., substantially co-axially, the cartridge 28 with the cartridge piercing needle 26c. In configurations where the adapter collar 30, 30' includes the cantilevered fingers 36, 36', the fingers 36, 36' protect the user against inadvertent needle stick injuries from the cartridge piercing needle 26c in the closed position. During insertion of the cartridge 28 into the interior pathway 26b, the cartridge 28 engages and deflects the fingers 36, 36' into the open position thereof upon advancement beyond the fingers 36, 36' and into engagement with the cartridge piercing needle 26c (Fig. 5).

[0045] In some embodiments, the injector 10 may be configured to be usable with cartridges 28 of different sizes. For example, as shown schematically, in Figs. 8A-9B, the injector 10 may be configured for use with at least two differently dimensioned cartridges: a first cartridge 28' and a second cartridge 28". Accordingly, the interior pathway 26b is sized, e.g., in diameter, to receive either of the first cartridge 28' or second cartridge 28". [0046] In one exemplary non-limiting embodiment, the interior pathway 26c may include at least two of the adapter collars 30, 30' mounted therein (two of the adapter collars 30, 30' shown in Figs. 8 A, 8B). As shown in the non-limiting example of Figs. 8 A and 8B, the first cartridge 28' may define a radially larger distal portion relative to the distal portion of the second cartridge 28", and the second cartridge 28" may define a radially larger proximal portion relative to the proximal portion of the first cartridge 28'. A first adapter collar 30, 30', therefore, is mounted distally within the interior pathway 26c relative to the second adapter collar 30, 30'.

[0047] The first, distal adapter collar 30, 30' is sized and positioned within the interior pathway 26b to permit advancement of either one of the first cartridge 28' or the second cartridge 28" therethrough upon insertion of that cartridge into the interior pathway 26b. As shown in Fig. 8B, the first, distal adapter collar 30, 30' is sized and positioned, however, to only engage a distal portion of the first cartridge 28' to stabilize the first cartridge 28' within the interior pathway 26b, and align the first cartridge 28' with the cartridge piercing needle 26c. That is, the ribs 34, 34' of the first, distal adapter collar 30, 30' are sized and dimensioned to engage the distal portion of the first cartridge 28', without interfering with the smaller distal portion of the second cartridge 28" if the second cartridge 28" was to be utilized with the injector 10.

[0048] Similarly, the second, proximal adapter collar 30, 30' is also sized and positioned within the interior pathway 26b to permit advancement of either one of the first cartridge 28' or the second cartridge 28" therethrough upon insertion of that cartridge into the interior pathway 26b. Conversely, however, as shown in Fig. 8A, the second, proximal adapter collar 30, 30' is sized and positioned to only engage a proximal portion of the second cartridge 28" to stabilize the second cartridge 28" within the interior pathway 26b, and to align the second cartridge 28" with the cartridge piercing needle 26c. That is, the ribs 34, 34' of the second, proximal adapter collar 30, 30' are sized and dimensioned to engage the proximal portion of the second cartridge 28", without interfering with the first cartridge 28' if the first cartridge 28' was to be utilized with the injector 10. Therefore, in the embodiment of Figs. 8 A, 8B, the second cartridge 28" is not obstructed by either of the adapter collars 30, 30' mounted within the interior pathway 26b, and the first cartridge 28' is also not obstructed by either of the adapter collars 30, 30' mounted within the interior pathway 26b. Either of the two cartridges 28', 28" is usable with the injector 10, however, as either cartridge 28', 28" may be stabilized within the interior pathway 26b and aligned with the cartridge piercing needle 26c.

[0049] In some embodiments, some of the adapter collars 30, 30' mounted within the interior pathway 26b, such as, for example, the distal-most adapter collar, may include the plurality of angularly spaced apart cantilevered fingers 36, 36' projecting from the disk 32 to assist in preventing contact between a user’s hands/fingers (or other of a user’s body parts) and the cartridge piercing needle 26c, and, therefore, assist in preventing needle stick injuries. Alternatively, all or none of the adapter collars 30, 30' mounted within the interior pathway 26b may include the cantilevered fingers 36, 36'.

[0050] In an alternative exemplary non-limiting embodiment, as shown in Figs. 9A, and 9B, the interior pathway may include solely the distal adapter collar 30, 30' as shown in Figs. 8A and 8B, configured in like manner as the distal adapter collar 30, 30' described with respect to Figs. 8A and 8B to stabilize the first cartridge 28' within the interior pathway 26b, and to align the first cartridge 28' with the cartridge piercing needle 26c (Fig. 9B). Conversely, the interior pathway 26b itself, i.e., the internal features thereof, may be configured to stabilize the second cartridge 28" within the interior pathway 26b, and to align the second cartridge 28" with the cartridge piercing needle 26c (Fig. 9A). For example, without limitation, the interior pathway 26b may be dimensioned or include a cartridge cradle, a cartridge track, combinations thereof, or the like (not shown) to receive and stabilize the cartridge 28 in the interior pathway 26b.

[0051] In one configuration, the injector 10 may be provided as a kit with a plurality of adapter collars 30, 30' removably mountable within the interior pathway 26b. The interior pathway 26b may be configured to receive any one of multiple different dimensioned cartridges 28, i.e., sized and dimensioned to receive the largest of those cartridges 28. Each adapter collar 30, 30' provided may be configured, i.e., sized and dimensioned, for use with a corresponding one of the multiple differently dimensioned cartridges 28, to engage a portion of the corresponding cartridge 28 (with the ribs 34, 34' thereof) to stabilize the cartridge 28 within the interior pathway 26b and align the cartridge 28 with the cartridge piercing needle 26c. Alternatively, or additionally, adapter collars 30, 30' provided may be configured to account for variations between cartridges 28 due to manufacturing tolerances. Accordingly, a user may mount a particular adapter collar 30, 30' within the interior pathway 26b to enable usage of the injector 10 with the respective corresponding cartridge 28 prior to inserting the corresponding cartridge 28 into the interior pathway 26b.

[0052] It will be appreciated by those skilled in the art that changes could be made to the embodiments described above without departing from the broad inventive concept thereof. It is understood, therefore, that this invention is not limited to the particular embodiments disclosed, but it is intended to cover modifications within the spirit and scope of the present invention, as set forth in the appended claims.