INOCULUM FORMED BY INOCULATING MICROORGANISM, AND METHOD FOR PRODUCING ANTIBIOTIC USING SAME

WIPO Patent Application WO/2015/053285

A1

　The objective of the present invention is to provide a method for more efficiently producing an antibiotic, in particular for omitting a pre-culturing step in the production of nosiheptide, and for simply and reliably collecting and seeding a fixed amount of microbial cells, whereby the production of the antibiotic can be made more efficient. The present invention is characterized by using, as an inoculum obtained by inoculation onto a solid carrier, an antibiotic-producing bacterium such as an actinobacterium belonging to the group Streptomyces sp. used in pre-culturing when manufacturing an antibiotic such as nosiheptide.

NANJOH YASUKO (JP)
KOGA HIROYASU (JP)
TSUNEMITSU TOSHIYA (JP)

PCT/JP2014/076851

April 16, 2015

October 07, 2014

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NIHON NOHYAKU CO LTD (JP)

C12N11/02; C12N1/14; C12P21/04

JPS6125495A	1986-02-04
JPS40880B
JP2000109495A	2000-04-18
JP2004305211A	2004-11-04

KAPETANOVIC, E. ET AL.: "Use of millet as a substrate for longterm conservation of oxytetracycline producing Streptomyces R6 strain isolates", MIKROBIOLOGIJA, vol. 8, no. 1, 1971, pages 135 - 144
BISEIBUTSU NO HOZONHO, 30 April 1978 (1978-04-30), pages 230
CUNDLIFFE, E. ET AL.: "The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism", JOURNAL OF GENERAL MICROBIOLOGY, vol. 126, no. 1, September 1981 (1981-09-01), pages 185 - 192, XP001246908

TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)

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