INORGANIC COMPOSITION WITH EXCELLENT PROPERTY OF GRADUALLY RELEASING ZINC ION, AND PRODUCTION METHOD THEREFOR

Title:

INORGANIC COMPOSITION WITH EXCELLENT PROPERTY OF GRADUALLY RELEASING ZINC ION, AND PRODUCTION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2018/105739

Kind Code:

A1

Abstract:

The present invention provides: an inorganic composition which is useful as a base for pharmaceuticals and has excellent stability; and a method for producing the inorganic composition. The inorganic composition contains at least one compound selected from the group consisting of zinc sulfate, zinc chloride, zinc carbonate, zinc hydroxide, and zinc oxide, and has a pH of 7.2 or higher but lower than 8.3. After a dissolution test of the inorganic composition performed by a stirring method, the amount of Zn2+ ions released therefrom is 0.1 μg/m2 or larger. This inorganic composition has the excellent property of gradually releasing zinc ions which makes the inorganic composition usable as a base for pharmaceuticals.

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Inventors:

ECHIZENYA YUKO (JP)
NAKATA YOSHIMI (JP)
UDAGAWA ETSUROU (JP)
YAMAMOTO OSAMU (JP)

Application Number:

PCT/JP2017/044225

Publication Date:

June 14, 2018

Filing Date:

December 08, 2017

Export Citation:

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Assignee:

JFE MINERAL CO LTD (JP)

International Classes:

A61K33/30; A61L15/18; A61P17/02

Domestic Patent References:

WO1996025913A1	1996-08-29
WO2003082229A1	2003-10-09
WO2016199907A1	2016-12-15

Foreign References:

JP2005524690A	2005-08-18
JP2004269372A	2004-09-30
JP2005515191A	2005-05-26
JP2004534560A	2004-11-18
JP2014511851A	2014-05-19
CN103479590A	2014-01-01
CN103622885A	2014-03-12
CN104546629A	2015-04-29
JP2004161684A	2004-06-10
JP2005006995A	2005-01-13
JP2016067416W	2016-06-10

Other References:

"skin disease treatment agents 262, 264 zinc oxide", DRUGS IN JAPAN ETHICAL DRUGS, 2008, pages 2, 3, XP009514845, ISBN: 978-4-8407-3863-7
WANG, M. M. ET AL.: "Mutagenicity of ZnO nanoparticles in mammalian cells: Role of physicochemical transformations under the aging process", NANOTOXICOLOGY, 13 February 2015 (2015-02-13), pages 1 - 11, XP055607670, ISSN: 1743-5404
See also references of EP 3552610A4

Attorney, Agent or Firm:

WATANABE Mochitoshi et al. (JP)

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