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Title:
INTEGRATION OF BIOCHEMICAL PROTOCOLS IN A CONTINUOUS FLOW MICROFLUIDIC DEVICE
Document Type and Number:
WIPO Patent Application WO2001007159
Kind Code:
A3
Abstract:
Provided is a microfluidic device comprising a microfluidic substrate comprising at least one pathway for sample flow; and at least one thermal transfer member which is capable of cycling between at least two temperatures. The thermal transfer member is adapted to heat at least a portion of the sample pathway while a sample is flowing along said at least a portion of said sample pathway. Provided also are methods of carrying out biochemical protocols using such a device.

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Inventors:
FOUILLET YVES (FR)
VAUCHIER CLAUDE (FR)
CLERC JEAN-FREDERIC (FR)
PEPONNET CHRISTINE (FR)
Application Number:
PCT/IB2000/001137
Publication Date:
May 25, 2001
Filing Date:
July 28, 2000
Export Citation:
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Assignee:
GENSET SA (FR)
COMMISSARIAT ENERGIE ATOMIQUE (FR)
FOUILLET YVES (FR)
VAUCHIER CLAUDE (FR)
CLERC JEAN FREDERIC (FR)
PEPONNET CHRISTINE (FR)
International Classes:
G01N33/53; B01L3/00; B01L7/00; B81B1/00; B81C1/00; C12M1/00; C12N15/09; C12Q1/68; G01N35/08; G01N37/00; B01L7/02; (IPC1-7): C12Q1/68; G01N35/08; B01L7/00; B01L3/00
Domestic Patent References:
WO2000023190A12000-04-27
WO1999041015A11999-08-19
WO1996015269A21996-05-23
WO1999039005A11999-08-05
Foreign References:
GB2325464A1998-11-25
EP0636413A21995-02-01
US5270183A1993-12-14
US5866345A1999-02-02
Other References:
KOPP ET AL: "chemical amplification:continuous flow PCR on a chip", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 280, no. 280, 15 May 1998 (1998-05-15), pages 1046 - 1048-1048, XP002107956, ISSN: 0036-8075
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