INTERMEDIATES FOR OPTICALLY ACTIVE PIPERIDINE DERIVATIVES AND PREPARATION METHODS THEREOF

Title:

INTERMEDIATES FOR OPTICALLY ACTIVE PIPERIDINE DERIVATIVES AND PREPARATION METHODS THEREOF

Document Type and Number:

WIPO Patent Application WO/2019/117550

Kind Code:

A1

Abstract:

A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.

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Inventors:

KWEON JAE HONG (KR)
KIM EUN SUN (KR)
LEE HYUK WOO (KR)
KO DONG HYUN (KR)
RYU CHAE YOUNG (KR)
CHOI KWANG DO (KR)
HEO SEUNGPYEONG (KR)

Application Number:

PCT/KR2018/015559

Publication Date:

June 20, 2019

Filing Date:

December 07, 2018

Export Citation:

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Assignee:

CJ HEALTHCARE CORP (KR)

International Classes:

C07D211/74; A61K31/45

Domestic Patent References:

WO2013021052A1	2013-02-14
WO2011159852A1	2011-12-22
WO2013116491A1	2013-08-08

Foreign References:

US20120041225A1	2012-02-16
KR20110036191A	2011-04-07

Other References: