Title:
INTESTINAL MUSCLE LAYER THINNING PREVENTING/TREATING COMPOSITION, DIARRHEA PREVENTING/TREATING COMPOSITION, AND WEANING STRESS ALLEVIATING COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2016/068186
Kind Code:
A1
Abstract:
[Problem] To provide a new intestinal muscle layer thinning preventing/treating composition, diarrhea preventing/treating composition, and weaning stress alleviating composition. [Solution] The present invention was achieved after confirming that a composition containing at least a lactic-acid bacterium (particularly, Streptococcus faecalis), a butyric-acid bacterium (particularly, Clostridium butyricum), and a saccharifying bacterium (particularly, Bacillus mesentericus) can reduce weaning stress by suppressing atrophy and increasing height of villi of intestinal tissues, suppressing thinning of intestinal muscle layers, preventing diarrhea after weaning, and improving intestinal health state.
Inventors:
HAYAKAWA TERUO (JP)
MASUDA TOMOHIDE (JP)
KUROSAWA DAISUKE (JP)
MASUDA TOMOHIDE (JP)
KUROSAWA DAISUKE (JP)
Application Number:
PCT/JP2015/080376
Publication Date:
May 06, 2016
Filing Date:
October 28, 2015
Export Citation:
Assignee:
TOA PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K35/744; A61K35/74; A61K35/742; A61P1/00; A61P1/12; A61P25/18
Foreign References:
| JP2014133736A | 2014-07-24 | |||
| JP2008255080A | 2008-10-23 |
Other References:
TERUHIKO YUYAMA ET AL.: "Effect of Pellet Type Probiotics Feeding on Growth of Calves", BULLETIN OF BEEF CATTLE SCIENCE, vol. 83, 2007, pages 11 - 19
TOMIYA UCHINO ET AL.: "Live Bacterial Drug (Biothree for Animals) for Canine Diarrhea", JAPANESE JOURNAL OF SMALL ANIMAL PRACTICE, vol. 14, no. 1, 1995, pages 17 - 23
HIROSHI NAKAMURA ET AL.: "Hiiku Buta ni Mirareta Rinyugo Tazokisei Hatsuiku Furyo Shokogun (PMWS", TOKYO-TO KACHIKU HOKEN EISEI GYOSEKI HAPPYOKAI SHUROKU, vol. 2007, 2008, pages 50 - 53
TAKAMITSU TSUKAHARA ET AL.: "The effect of Enterococcus faecalis cell preparation ( EC -12) against the diarrhea in the nursing and weaning piglets under the clinical condition", PROCEEDINGS OF THE JAPANESE PIG VETERINARY SOCIETY, vol. 48, 2006, pages 19 - 23
TOSHIO KITAJO ET AL.: "Influence of administration of living bacterial preparation on the growth of suckling pigs", ANIMAL- HUSBANDRY, vol. 43, no. 3, 1989, pages 372 - 374
TERUJI YAMAMOTO ET AL.: "Efficacy tests of diarrhea prevention on the therapeutic agents for digestive function disorders in weaning piglets", JOURNAL OF CLINICAL VETERINARY MEDICINE, vol. 12, no. 10, 1994, pages 69 - 71
TOMIYA UCHINO ET AL.: "Live Bacterial Drug (Biothree for Animals) for Canine Diarrhea", JAPANESE JOURNAL OF SMALL ANIMAL PRACTICE, vol. 14, no. 1, 1995, pages 17 - 23
HIROSHI NAKAMURA ET AL.: "Hiiku Buta ni Mirareta Rinyugo Tazokisei Hatsuiku Furyo Shokogun (PMWS", TOKYO-TO KACHIKU HOKEN EISEI GYOSEKI HAPPYOKAI SHUROKU, vol. 2007, 2008, pages 50 - 53
TAKAMITSU TSUKAHARA ET AL.: "The effect of Enterococcus faecalis cell preparation ( EC -12) against the diarrhea in the nursing and weaning piglets under the clinical condition", PROCEEDINGS OF THE JAPANESE PIG VETERINARY SOCIETY, vol. 48, 2006, pages 19 - 23
TOSHIO KITAJO ET AL.: "Influence of administration of living bacterial preparation on the growth of suckling pigs", ANIMAL- HUSBANDRY, vol. 43, no. 3, 1989, pages 372 - 374
TERUJI YAMAMOTO ET AL.: "Efficacy tests of diarrhea prevention on the therapeutic agents for digestive function disorders in weaning piglets", JOURNAL OF CLINICAL VETERINARY MEDICINE, vol. 12, no. 10, 1994, pages 69 - 71
Attorney, Agent or Firm:
SHOJI, Takashi et al. (JP)
Takashi Shoji (JP)
Takashi Shoji (JP)
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