Title:
INTESTINAL TRACT-PROTECTING AGENT CONTAINING HYDROXYLATED FATTY ACID
Document Type and Number:
WIPO Patent Application WO/2014/129384
Kind Code:
A1
Abstract:
Provided are an intestinal tract-protecting agent and an agent for preventing or ameliorating a disease caused by an injury in the barrier function of the intestinal tract, which comprise a hydroxylated fatty acid, in particular a hydroxylated unsaturated fatty acid, having hydroxyl group(s) at the 10- and/or 12-positions, said hydroxylated fatty acid being an intermediate in unsaturated fatty acid metabolism by a lactic acid bacterium.
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Inventors:
OGAWA JUN (JP)
KISHINO SHIGENOBU (JP)
YONEJIMA YASUNORI (JP)
KISHINO SHIGENOBU (JP)
YONEJIMA YASUNORI (JP)
Application Number:
PCT/JP2014/053383
Publication Date:
August 28, 2014
Filing Date:
February 13, 2014
Export Citation:
Assignee:
UNIV KYOTO (JP)
NITTO PHARMACEUTICAL IND LTD (JP)
NITTO PHARMACEUTICAL IND LTD (JP)
International Classes:
A61K31/20; A23K1/16; A23K1/165; A23L1/30; A61K31/201; A61P1/00; A61P1/04; C07C59/42
Domestic Patent References:
| WO1999016435A1 | 1999-04-08 | |||
| WO2010117194A2 | 2010-10-14 |
Foreign References:
| JP2003073286A | 2003-03-12 | |||
| JPH09241177A | 1997-09-16 | |||
| JP2012108928A | 2012-05-10 | |||
| JP2007259712A | 2007-10-11 |
Other References:
See also references of EP 2959897A4
NUSRAT A, AM J PHYSIOL GASTROINTEST LIVER PHYSIOL., vol. 279, no. 5, 2000, pages G851 - G857
HA YL, CARCINOGENESIS, vol. 8, no. 12, 1987, pages 1881 - 1887
CLEMENT IP, CANCER RES., vol. 51, 1991, pages 6118 - 6124
KISUN NL, ATHEROSCLEROSIS, vol. 108, 1994, pages 19 - 25
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 416, 2011, pages 188 - 193
NUSRAT A, AM J PHYSIOL GASTROINTEST LIVER PHYSIOL., vol. 279, no. 5, 2000, pages G851 - G857
HA YL, CARCINOGENESIS, vol. 8, no. 12, 1987, pages 1881 - 1887
CLEMENT IP, CANCER RES., vol. 51, 1991, pages 6118 - 6124
KISUN NL, ATHEROSCLEROSIS, vol. 108, 1994, pages 19 - 25
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 416, 2011, pages 188 - 193
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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