Title:
INTRANASAL DESMOPRESSIN ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO/2010/075266
Kind Code:
A3
Abstract:
Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control.
Inventors:
FEIN SEYMOUR (US)
Application Number:
PCT/US2009/068962
Publication Date:
January 06, 2011
Filing Date:
December 21, 2009
Export Citation:
Assignee:
SERENITY PHARMACEUTICALS CORP (US)
FEIN SEYMOUR (US)
FEIN SEYMOUR (US)
International Classes:
A61K9/00; A61K31/11; A61K31/4025; A61K38/095; A61M11/02; A61M15/00; A61M15/08
Domestic Patent References:
| WO1995001183A1 | 1995-01-12 |
Foreign References:
| US20050158247A1 | 2005-07-21 |
Other References:
LAW S L ET AL: "Preparation of desmopressin-containing liposomes for intranasal delivery", JOURNAL OF CONTROLLED RELEASE 20010223 NL LNKD- DOI:10.1016/S0168-3659(00)00369-2, vol. 70, no. 3, 23 February 2001 (2001-02-23), pages 375 - 382, XP002608762, ISSN: 0168-3659
FABRIZIO B ET AL: "In vitro permeation of desmopressin across rabbit nasal mucosa from liquid nasal sprays: The enhancing effect of potassium sorbate", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, ELSEVIER, AMSTERDAM, NL, vol. 37, no. 1, 11 April 2009 (2009-04-11), pages 36 - 42, XP025992154, ISSN: 0928-0987, [retrieved on 20081231], DOI: DOI:10.1016/J.EJPS.2008.12.015
FABRIZIO B ET AL: "In vitro permeation of desmopressin across rabbit nasal mucosa from liquid nasal sprays: The enhancing effect of potassium sorbate", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, ELSEVIER, AMSTERDAM, NL, vol. 37, no. 1, 11 April 2009 (2009-04-11), pages 36 - 42, XP025992154, ISSN: 0928-0987, [retrieved on 20081231], DOI: DOI:10.1016/J.EJPS.2008.12.015
Attorney, Agent or Firm:
FAIRCHILD, Brian, A. et al. (Exchange PlaceBoston, MA, US)
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