Title:
INTRAOPERATIVE GUIDANCE SYSTEM FOR TUMOR SURGERY
Document Type and Number:
WIPO Patent Application WO/2015/123316
Kind Code:
A3
Abstract:
The current invention pertains to a system and methods of identifying a site in a tissue of a patient as neoplastic or normal. The system comprises a source of electromagnetic signals; an optical probe which delivers the electromagnetic signals to a working end of the probe; a spectrometer which acquires diffuse reflectance electromagnetic signals returned from the site probed by the optical probe. The spectrometer processes the diffuse reflectance signals to produce a diffuse reflectance spectra which is transmitted to a system controller programmed to analyze the diffuse reflectance spectra to calculate hemoglobin concentration, hemoglobin oxygenation, and/or diffuse reflectance intensity of signals having wavelength of about 700 nm. These parameters are used to identify the site as neoplastic or normal. The system of current invention can be used in identifying neoplastic sites in brain in an intraoperative manner, for example, during a pediatric brain surgery.
Inventors:
LIN WEI-CHIANG (US)
SONG YINCHEN (US)
SONG YINCHEN (US)
Application Number:
PCT/US2015/015444
Publication Date:
October 08, 2015
Filing Date:
February 11, 2015
Export Citation:
Assignee:
FLORIDA INT UNIV BOARD TRUSTEES (US)
International Classes:
A61B5/05; A61B5/053
Foreign References:
| US20100198080A1 | 2010-08-05 | |||
| US20130338739A1 | 2013-12-19 | |||
| US20040044287A1 | 2004-03-04 | |||
| US20110105865A1 | 2011-05-05 | |||
| US20020058865A1 | 2002-05-16 |
Attorney, Agent or Firm:
LLOYD, Jeff et al. (Lloyd & EisenschenkPo Box 14295, Gainesville FL, US)
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