Title:
INTRAVITAL STAINING CONTRAST MEDIA USING POLYURONIC ACID AS CARRIER, AND PREPARATION METHOD AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/045508
Kind Code:
A1
Abstract:
Disclosed are a macromolecular intravital staining contrast media, and a preparation method and use thereof. The contrast media uses a polyuronic acid as a carrier, a mannose or mannose derivative as a mannose receptor (MBP) recognition group, and a paramagnetic metal ion chelate as a nuclear magnetic resonance imaging group, which is used for the sentinel lymph node location before operating on breast cancer, head and neck cancer, melanomas and so on, and satisfies the biopsy and nuclear magnetic resonance imaging, and is a bifunctional lymphatic targeted contrast media.
Inventors:
JIANG TAO (CN)
WAN SHENGBIAO (CN)
ZHANG NAN (CN)
ZHAO MINGLIANG (CN)
WAN SHENGBIAO (CN)
ZHANG NAN (CN)
ZHAO MINGLIANG (CN)
Application Number:
PCT/CN2016/095825
Publication Date:
March 23, 2017
Filing Date:
August 18, 2016
Export Citation:
Assignee:
OCEAN UNIV CHINA (CN)
International Classes:
A61K49/12; A61P43/00
Foreign References:
| CN105148291A | 2015-12-16 | |||
| CN102504603A | 2012-06-20 | |||
| CN101325978A | 2008-12-17 | |||
| CN101619106A | 2010-01-06 |
Attorney, Agent or Firm:
QINGDAO LAWSCI INTELLECTUAL PROPERTY LAW OFFICE (CN)
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