Title:
IRAK INHIBITORS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/011911
Kind Code:
A3
Abstract:
The present invention provides furano- and pyrrolo- pyrimidine and pyridine compounds, compositions thereof, and methods of using the same.
Inventors:
HARRIMAN GERALDINE C (US)
ROMERO DONNA L (US)
MASSE CRAIG E (US)
ROBINSON SHAUGHNESSY (US)
WESSEL MATTHEW DAVID (US)
GREENWOOD JEREMY ROBERT (US)
ROMERO DONNA L (US)
MASSE CRAIG E (US)
ROBINSON SHAUGHNESSY (US)
WESSEL MATTHEW DAVID (US)
GREENWOOD JEREMY ROBERT (US)
Application Number:
PCT/US2013/050120
Publication Date:
July 16, 2015
Filing Date:
July 11, 2013
Export Citation:
Assignee:
NIMBUS IRIS INC (US)
International Classes:
A61K31/505; A61K31/519; A61P35/00
Domestic Patent References:
| WO2012007375A1 | 2012-01-19 |
Foreign References:
| US8058285B2 | 2011-11-15 | |||
| US20100143341A1 | 2010-06-10 | |||
| US6297238B1 | 2001-10-02 |
Other References:
NGO, VN ET AL.: "Oncogenically active MYD88 mutations in human lymphoma.", NATURE, vol. 470, no. 7332, 22 December 2010 (2010-12-22), pages 115 - 119, Retrieved from the Internet [retrieved on 20131129]
SONG, KW ET AL.: "The kinase activities of Interleukin-1 receptor associated kinase ( IRAK )-1 and 4 are redundant in the control of Inflammatory cytokine expression in human cells.", MOL IMMUNOL, vol. 46, no. 7, 31 January 2009 (2009-01-31), pages 1458 - 1466, Retrieved from the Internet [retrieved on 20131129]
SONG, KW ET AL.: "The kinase activities of Interleukin-1 receptor associated kinase ( IRAK )-1 and 4 are redundant in the control of Inflammatory cytokine expression in human cells.", MOL IMMUNOL, vol. 46, no. 7, 31 January 2009 (2009-01-31), pages 1458 - 1466, Retrieved from the Internet
Attorney, Agent or Firm:
MCLEAN, Thomas H. et al. (Hall & Stewart LLPTwo International Plac, Boston Massachusetts, US)
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