Title:
ISOLATED HUMAN HEPSIN/46 PROTEINS, NUCLEIC ACID MOLECULES ENCODING HUMAN HEPSIN/46 PROTEINS, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2004035733
Kind Code:
A3
Abstract:
The present invention provides hepsin/46 protein, a soluble form of hepsin lacking the transmembrane region. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying molecules that interacting with the protease peptides, and methods of identifying modulators of the protease peptides.
Inventors:
CHAN HEDY (US)
BOWMAN KIRSTA (US)
GJERSTAD ERIK (US)
BOWMAN KIRSTA (US)
GJERSTAD ERIK (US)
Application Number:
PCT/US2003/027440
Publication Date:
October 21, 2004
Filing Date:
September 04, 2003
Export Citation:
Assignee:
APPLERA CORP (US)
CHAN HEDY (US)
BOWMAN KIRSTA (US)
GJERSTAD ERIK (US)
CHAN HEDY (US)
BOWMAN KIRSTA (US)
GJERSTAD ERIK (US)
International Classes:
C07H21/04; C12N9/64; C12Q1/68; (IPC1-7): C12N9/64; C12N9/76; C12Q1/37; G01N33/53
Domestic Patent References:
| WO2001057194A2 | 2001-08-09 |
Other References:
LEYTUS ET AL: "A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human iver and hepatoma cells", BIOCHEMISTRY, vol. 27, 1988, pages 1067 - 1074, XP002080091
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