Title:
ISOLATED T CELL RECEPTORS AND METHODS OF USE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2015/160928
Kind Code:
A3
Abstract:
Provided are isolated TCRs, TCR-like molecules, and portions thereof that bind to phosphopeptide-HLA-A2 complexes. The isolated TCRs, TCR-like molecules, or portions are optionally soluble TCRs, TCR-like molecules, or portions. Also provided are isolated nucleic acids encoding the disclosed TCRs, TCR-like molecules, or portions; host cells that contain the disclosed TCRs, TCR-like molecules, or portions; pharmaceutical compositions that include the disclosed TCRs, TCR-like molecules, portions, nucleic acids, and/or T cells; kits; and methods of using the same.
Inventors:
ZARLING ANGELA (US)
ENGELHARD VICTOR H (US)
CUMMINGS KARA L (US)
OBENG REBECCA C (US)
ENGELHARD VICTOR H (US)
CUMMINGS KARA L (US)
OBENG REBECCA C (US)
Application Number:
PCT/US2015/025942
Publication Date:
December 10, 2015
Filing Date:
April 15, 2015
Export Citation:
Assignee:
UNIV VIRGINIA PATENT FOUND (US)
International Classes:
A61K38/08
Domestic Patent References:
| WO2014036562A2 | 2014-03-06 | |||
| WO2014039675A2 | 2014-03-13 | |||
| WO2013162651A1 | 2013-10-31 |
Foreign References:
| US20090304657A1 | 2009-12-10 | |||
| US20130259883A1 | 2013-10-03 |
Other References:
See also references of EP 3137100A4
Attorney, Agent or Firm:
PERKINS, Christopher, P. (WILSON TAYLOR & HUNT, P.A.,Suite 1200, University Tower,3100 Tower Boulevar, Durham NC, US)
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