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Title:
ISOPROPYL ALCOHOL-PRODUCING BACTERIUM HAVING IMPROVED PRODUCTIVITY BY GNTR DESTRUCTION
Document Type and Number:
WIPO Patent Application WO/2012/020833
Kind Code:
A1
Abstract:
Provided is an isopropyl alcohol-producing Escherichia coli, which comprises: a system that produces isopropyl alcohol together with the deactivation of the transcription regulator GntR; and a coenzyme group having an enzymatic activity manifestation pattern that maintains or reinforces the isopropyl alcohol production that accompanies the deactivation of GntR. Also provided is a method for producing isopropyl alcohol, which includes the production of isopropyl alcohol from a plant-derived starting material using this isopropyl alcohol-producing Escherichia coli. Further provided is a method for producing acetone, which includes bringing the isopropyl alcohol obtained by the above-mentioned production method into contact with a compound oxide that contains zinc oxide and at least one oxide of group 4 of the Periodic Table of Elements and that has been prepared by coprecipitation. Additionally provided is a method for producing propylene, which includes bringing the isopropyl alcohol and acetone obtained by the above-mentioned production methods into contact with a solid acid substance and a hydrogenation catalyst containing Cu as the catalysts.

Inventors:
AMANO KOH (JP)
SHIRAI TOMOKAZU (JP)
TAKAHASHI HITOSHI (JP)
HIRANO JUNICHIRO (JP)
MATSUMOTO YOSHIKO (JP)
TAKEBAYASHI NOZOMI (JP)
WADA MITSUFUMI (JP)
SHIMIZU HIROSHI (JP)
FURUSAWA CHIKARA (JP)
HIRASAWA TAKASHI (JP)
Application Number:
PCT/JP2011/068402
Publication Date:
February 16, 2012
Filing Date:
August 11, 2011
Export Citation:
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Assignee:
MITSUI CHEMICALS INC (JP)
AMANO KOH (JP)
SHIRAI TOMOKAZU (JP)
TAKAHASHI HITOSHI (JP)
HIRANO JUNICHIRO (JP)
MATSUMOTO YOSHIKO (JP)
TAKEBAYASHI NOZOMI (JP)
WADA MITSUFUMI (JP)
SHIMIZU HIROSHI (JP)
FURUSAWA CHIKARA (JP)
HIRASAWA TAKASHI (JP)
International Classes:
C12N1/21; C12N15/09; C12P7/04
Domestic Patent References:
WO2009103026A12009-08-20
WO2009008377A12009-01-15
WO2009028582A12009-03-05
WO2009049274A22009-04-16
WO2009008377A12009-01-15
WO2009049274A22009-04-16
WO2009028582A12009-03-05
WO2009103026A12009-08-20
WO2009024721A22009-02-26
Foreign References:
JPH05260979A1993-10-12
JPH0753433A1995-02-28
JPH11335315A1999-12-07
JPH1135498A1999-02-09
JPH1135497A1999-02-09
JPH05260979A1993-10-12
JPH0753433A1995-02-28
JPH11335315A1999-12-07
GB665376A1952-01-23
JPH02174737A1990-07-06
DD84378A
JP2786272B21998-08-13
JP2010181150A2010-08-12
JP2011049531A2011-03-07
Other References:
WADA, M. ET AL.: "Production of D-lactic acid, isopropanol and glycolic acid", BIO INDUSTRY, vol. 27, no. 11, December 2010 (2010-12-01), pages 27 - 31, XP008167950
APPL. ENVIRON. BIOTECHNOL., vol. 73, no. 24, 2007, pages 7814 - 7818
APPL. MICROBIOL. BIOTECHNOL., vol. 77, no. 6, 2008, pages 1219 - 1224
J. BACTERIOL., vol. 161, 1985, pages 1219 - 1221
J. BACTERIOL., vol. 177, 1995, pages 1511 - 1519
PROC. NATL. ACAD. SCI. U.S.A, vol. 97, 2000, pages 6640 - 6645
SAMBROOK, J. ET AL.: "Molecular Cloning A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
LAUREN SALLUS JENKINS, JOURNAL OF BACETERIOLOGY, vol. 169, pages 42 - 52
Attorney, Agent or Firm:
NAKAJIMA, Jun et al. (JP)
Nakajima 淳 (JP)
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