Title:
ISOQUINOLINE DERIVATIVES HAVING KINASAE INHIBITORY ACTIVITY AND DRUGS CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO/2004/024717
Kind Code:
A1
Abstract:
It is intended to provide a compound which is useful in treating a disease mediated by Rho kinase because of having an Rho kinase inhibitory effect. Namely, a compound of the following general formula (I), its pharmaceutically acceptable salt or a solvate thereof: (I) wherein Q represents phenyl, pyridyl, pyrrolyl, thienyl or furyl optionally having one or two substituents selected from among halogens, alkyls, nitro and amino; and p is 2 or 3.
Inventors:
IWAKUBO MASAYUKI (JP)
OKADA YUJI (JP)
OKADA YUJI (JP)
Application Number:
PCT/JP2003/011733
Publication Date:
March 25, 2004
Filing Date:
September 12, 2003
Export Citation:
Assignee:
KIRIN BREWERY (JP)
IWAKUBO MASAYUKI (JP)
OKADA YUJI (JP)
IWAKUBO MASAYUKI (JP)
OKADA YUJI (JP)
International Classes:
A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P15/00; A61P15/02; A61P15/10; A61P19/10; A61P27/00; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P37/00; A61P43/00; C07D401/12; C07D401/14; C07D405/14; C07D409/14; (IPC1-7): C07D401/12; A61K31/4725; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P15/00; A61P15/02; A61P15/10; A61P19/10; A61P27/00; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P37/00; A61P43/00; C07D401/14; C07D405/14; C07D409/14
Domestic Patent References:
| WO2001056988A1 | 2001-08-09 | |||
| WO1998006433A1 | 1998-02-19 |
Attorney, Agent or Firm:
Yoshitake, Kenji (Room 323 Fuji Bldg., 2-3, Marunouchi 3-chom, Chiyoda-ku Tokyo, JP)
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