Title:
KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE
Document Type and Number:
WIPO Patent Application WO2004080377
Kind Code:
A3
Abstract:
This invention relates to compounds of the general formula (I) useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.
Inventors:
BROWN WILLIAM DALBY (DK)
TEUBER LENE (DK)
DAHL BJARNE H (DK)
TEUBER LENE (DK)
DAHL BJARNE H (DK)
Application Number:
PCT/EP2004/050290
Publication Date:
November 04, 2004
Filing Date:
March 11, 2004
Export Citation:
Assignee:
NEUROSEARCH AS (DK)
BROWN WILLIAM DALBY (DK)
TEUBER LENE (DK)
DAHL BJARNE H (DK)
BROWN WILLIAM DALBY (DK)
TEUBER LENE (DK)
DAHL BJARNE H (DK)
International Classes:
C07C65/05; C07C65/21; C07C65/24; C07C65/28; C07C65/40; C07C69/86; C07C205/34; C07C205/38; C07C215/68; C07C215/76; C07C229/64; C07C233/25; C07C233/43; C07C233/55; C07C233/56; C07C233/90; C07C235/60; C07C243/38; C07C251/48; C07C255/54; C07C255/59; C07D209/12; C07D209/14; C07D211/22; C07D211/46; C07D213/30; C07D213/68; C07D215/14; C07D249/08; C07D257/04; C07D261/08; C07D271/07; C07D291/04; C07D307/42; C07D307/64; C07D309/12; C07D317/54; C07D317/58; C07D319/18; C07D321/10; C07D333/16; C07D271/06; (IPC1-7): C07C65/21; C07C65/24; C07C65/28; C07C65/40; C07C205/34; C07C205/38; C07C215/68; C07C215/76; C07C229/64; C07C233/25; C07C233/43; C07C233/55; C07C243/38; C07C255/54; C07C311/29
Domestic Patent References:
| WO2001010380A2 | 2001-02-15 | |||
| WO2002062295A2 | 2002-08-15 | |||
| WO1996003380A1 | 1996-02-08 |
Foreign References:
| US2852557A | 1958-09-16 | |||
| US5753648A | 1998-05-19 | |||
| DE2232462A1 | 1974-01-10 |
Other References:
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SUGIYAMA ET AL.: "Preparation of salicylic acid-contg. thiazole derivatives as antiinflammatory agents", XP002292398, retrieved from STN Database accession no. 1992:612486
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292399, Database accession no. BRN 4865050
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292400, Database accession no. BRN 2653068
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292401, Database accession no. BRN 8724243
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292402, Database accession no. BRN 2652765
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292403, Database accession no. BRN 5869057
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292404, Database accession no. BRN 5869062
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292405, Database accession no. BRN 3318003
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292406, Database accession no. BRN 1104542
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292407, Database accession no. BRN 1825682
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292408, Database accession no. BRN 208772
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292409, Database accession no. BRN 2865481
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292410, Database accession no. REACTION ID 4725290
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292411, Database accession no. BRN 5033009
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292412, Database accession no. BRN 37756
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292413, Database accession no. BRN 6983888
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292414, Database accession no. BRN 3404241
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292415, Database accession no. BRN 2096811
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292416, Database accession no. BRN 8482080
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292399, Database accession no. BRN 4865050
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292400, Database accession no. BRN 2653068
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292401, Database accession no. BRN 8724243
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292402, Database accession no. BRN 2652765
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292403, Database accession no. BRN 5869057
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292404, Database accession no. BRN 5869062
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292405, Database accession no. BRN 3318003
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292406, Database accession no. BRN 1104542
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292407, Database accession no. BRN 1825682
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292408, Database accession no. BRN 208772
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292409, Database accession no. BRN 2865481
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292410, Database accession no. REACTION ID 4725290
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292411, Database accession no. BRN 5033009
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292412, Database accession no. BRN 37756
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292413, Database accession no. BRN 6983888
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292414, Database accession no. BRN 3404241
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292415, Database accession no. BRN 2096811
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002292416, Database accession no. BRN 8482080
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