KDR PEPTIDES AND VACCINES CONTAINING THE SAME

WIPO Patent Application WO/2004/024766

A1

It is intended to provide a nonapeptide selected from among peptides comprising the amino acid sequences represented by SEQ ID NOS:2, 3, 5, 8, 11 and 12; a nonapeptide or a decapeptide selected from among peptides comprising the amino acid sequences represented by SEQ ID NOS:29, 30, 33, 34, 40 and 46; a peptide having an amino acid sequence derived from any of the above amino acid sequences by substitution or addition of one to several amino acids and being capable of inducing cytotoxic T cells; and drugs containing such a peptide for treating or preventing tumor. These peptides are usable as vaccines.

TAHARA HIDEAKI (JP)
WADA SATOSHI (JP)
TSUNODA TAKUYA (JP)

PCT/JP2003/011722

March 25, 2004

September 12, 2003

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ONCOTHERAPY SCIENCE INC (JP)
TAHARA HIDEAKI (JP)
WADA SATOSHI (JP)
TSUNODA TAKUYA (JP)

A61K39/00; A61P3/10; A61P9/10; A61P17/06; A61P27/02; A61P29/00; A61P35/00; A61P35/04; C07K14/705; C07K14/71; C12N5/07; C12N5/0783; C12N5/09; C12N15/12; (IPC1-7): C07K14/705; C12N15/12; C12N5/00; A61K38/17; A61K39/00; A61P3/10; A61P9/10; A61P17/06; A61P27/02; A61P29/00; A61P35/00; A61P35/04

WO1999059636A1	1999-11-25
WO1999040118A1	1999-08-12
WO1998031794A1	1998-07-23
WO2002056907A2	2002-07-25
WO1999043801A1	1999-09-02

LI Y. ET AL.: "Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis", J. EXP. MED., vol. 195, no. 12, June 2002 (2002-06-01), pages 1575 - 1584, XP002973897
THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 195, no. 12, 2002, pages 1575 - 1584
See also references of EP 1548032A4

Shimizu, Hatsushi (1-1-1 Oroshi-mach, Tsuchiura-shi Ibaraki, JP)

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