KELOID THERAPEUTIC AGENT - UNIV SAPPORO MEDICAL

Title:

KELOID THERAPEUTIC AGENT

Document Type and Number:

WIPO Patent Application WO/2012/105706

Kind Code:

A1

Abstract:

The present invention relates to a composition for inhibiting the proliferation of a keloid fibroblast, which contains a polyphenol represented by formula (I).

Inventors:

IKEDA KANAE (JP)
TORIGOE TOSHIHIKO (JP)
MATSUMOTO YOSHITAKA (JP)
FUJITA TATSUYA (JP)
YOTSUYANAGI TAKATOSHI (JP)
SATO NORIYUKI (JP)

Application Number:

PCT/JP2012/052559

Publication Date:

August 09, 2012

Filing Date:

February 03, 2012

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Assignee:

UNIV SAPPORO MEDICAL (JP)
IKEDA KANAE (JP)
TORIGOE TOSHIHIKO (JP)
MATSUMOTO YOSHITAKA (JP)
FUJITA TATSUYA (JP)
YOTSUYANAGI TAKATOSHI (JP)
SATO NORIYUKI (JP)

International Classes:

A61K31/05; A61P17/00

Domestic Patent References:

WO2001043705A2

2001-06-21

Foreign References:

JP2007084446A

2007-04-05

Other References:

PHAN,T.T. ET AL.: "Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring", J TRAUMA, vol. 54, no. 6, 2003, pages 1212 - 24
PHAN,T.T. ET AL.: "Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars", J DERMATOL SCI, vol. 33, no. 3, 2003, pages 192 - 4

Attorney, Agent or Firm:

KATSUNUMA Hirohito et al. (JP)
Katsunuma Hirohito (JP)

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