Title:
KETOLIDES HAVING ANTIBACTERIAL ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2018/067663
Kind Code:
A3
Abstract:
The present invention relates to ketolide compounds of Formula I. The compounds have good anti-microbial activities, reduced inhibition of cytochrome P4503 A4 (CYP3 A4), and acceptable safety of co-administration of other drugs. The present invention also relates to a pharmaceutical composition comprising compounds of Formula I and the method of treating anti-microbial infection by administering the compounds. Oral administration is a preferred route of administration.
Inventors:
SERGIO LOCIURO (CH)
ISLAM KHALID (CH)
ISLAM KHALID (CH)
Application Number:
PCT/US2017/055079
Publication Date:
May 16, 2019
Filing Date:
October 04, 2017
Export Citation:
Assignee:
BIOPHARMATI SA (CH)
International Classes:
A61K31/4709; A61K31/7048; A61P31/00; C07H17/08
Domestic Patent References:
| WO2014049356A1 | 2014-04-03 |
Foreign References:
| US7332476B2 | 2008-02-19 | |||
| US20050153905A1 | 2005-07-14 | |||
| US7462600B2 | 2008-12-09 |
Other References:
DATABASE PubChem Compound 12 June 2008 (2008-06-12), ANONYMOUS: "Compound Summary for SID 79844006 - C12020", XP055608695, retrieved from NCBI Database accession no. SID 79844006
See also references of EP 3522896A4
See also references of EP 3522896A4
Attorney, Agent or Firm:
KUNG, Viola T. et al. (US)
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