Title:
KINASE INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/101293
Kind Code:
A1
Abstract:
The present invention relates to a CDK4/6 kinase inhibitor, and a pharmaceutically acceptable salt, ester and solvate thereof or their stereoisomers; and also relates to a pharmaceutical preparation, pharmaceutical composition and kits which contain the CDK4/6 kinase inhibitor and the pharmaceutically acceptable salt, ester and solvate thereof or their stereoisomers; and the uses of the CDK4/6 kinase inhibitor and the pharmaceutically acceptable salt, ester and solvate thereof or their stereoisomers. For example, the compound of the invention can be used for reducing or inhibiting the CDK4/6 kinase activity in cells and/or treating and/or preventing cancer-related diseases mediated by the CDK4/6 kinase.
Inventors:
WU FRANK (CN)
CHEN BO (CN)
CHEN BO (CN)
Application Number:
PCT/CN2014/095615
Publication Date:
July 09, 2015
Filing Date:
December 30, 2014
Export Citation:
Assignee:
XUANZHU PHARMA CO LTD (CN)
International Classes:
C07D401/14; A61K31/496; A61K31/506; A61K31/5377; A61K31/5383; A61K31/5386; A61P35/00; C07D401/04; C07D471/08; C07D471/10; C07D487/04; C07D487/08; C07D487/10; C07D498/04; C07D498/08
Foreign References:
| CN102264725A | 2011-11-30 | |||
| CN102186856A | 2011-09-14 | |||
| CN102264725A | 2011-11-30 | |||
| CN101001857A | 2007-07-18 |
Other References:
See also references of EP 3091008A4
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
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