Title:
Aβ KIT, DETECTION METHOD AND USE
Document Type and Number:
WIPO Patent Application WO/2019/095403
Kind Code:
A1
Abstract:
Provided is a detection kit for an amyloid-β (Aβ) peptide. The kit comprises an anti-hemoglobin (Hb) antibody and an anti-Aβ antibody, wherein the anti-Hb antibody is a capture antibody and is used for capturing Hb, and the anti-Aβ antibody is a detection antibody and is used for detecting the content of Aβ binding to Hb. The kit is suitable for the quantitative detection of the content of all Aβs binding to Hb, comprising the quantitative detection of the content of Aβ binding to Hb in peripheral blood erythrocytes; and the kit is suitable for screening large-scale populations, and can solve the problem of the contamination of samples caused by hemolysis that is present in the existing technique of detecting Aβ from cerebrospinal fluid, plasma and serum samples.
Inventors:
YU SHUN (CN)
YANG WEIWEI (CN)
LI XIN (CN)
YANG WEIWEI (CN)
LI XIN (CN)
Application Number:
PCT/CN2017/112086
Publication Date:
May 23, 2019
Filing Date:
November 21, 2017
Export Citation:
Assignee:
XUANWU HOSPITAL OF CAPITAL MEDICAL UNIV (CN)
International Classes:
G01N33/68
Domestic Patent References:
| WO2011130377A2 | 2011-10-20 |
Foreign References:
| CN104215777A | 2014-12-17 | |||
| CN104215779A | 2014-12-17 | |||
| CN102076714A | 2011-05-25 |
Attorney, Agent or Firm:
BEIJING BRIGHT IP AGENCY CO., LTD. (CN)
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