Title:
KIT, DEVICE AND METHOD FOR DETECTING PROSTATE CANCER
Document Type and Number:
WIPO Patent Application WO/2020/032228
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a kit or device for use in the detection of prostate cancer; and a method for detecting prostate cancer. The present invention provides: a kit or device for use in the detection of prostate cancer, which includes a nucleic acid capable of binding specifically to miRNA or a complementary strand thereof in a sample from a subject; and a method for detecting prostate cancer, which comprises measuring the miRNA in vitro.
Inventors:
YOSHIMOTO MAKIKO (JP)
SUDO HIROKO (JP)
MIYANO ATSUKO (JP)
KOZONO SATOKO (JP)
OCHIYA TAKAHIRO (JP)
FUJIMOTO HIROYUKI (JP)
URABE FUMIHIKO (JP)
MATSUZAKI JUNTARO (JP)
SUDO HIROKO (JP)
MIYANO ATSUKO (JP)
KOZONO SATOKO (JP)
OCHIYA TAKAHIRO (JP)
FUJIMOTO HIROYUKI (JP)
URABE FUMIHIKO (JP)
MATSUZAKI JUNTARO (JP)
Application Number:
PCT/JP2019/031550
Publication Date:
February 13, 2020
Filing Date:
August 09, 2019
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
NAT CANCER CENTER JAPAN (JP)
NAT CANCER CENTER JAPAN (JP)
International Classes:
C12Q1/6886; C12N15/09; G01N33/53; G01N37/00; C12N15/11
Domestic Patent References:
| WO2015194615A1 | 2015-12-23 | |||
| WO2015194627A1 | 2015-12-23 | |||
| WO2015190584A1 | 2015-12-17 | |||
| WO2012063894A1 | 2012-05-18 | |||
| WO2018199275A1 | 2018-11-01 | |||
| WO2015190584A1 | 2015-12-17 |
Foreign References:
| JP2017521051A | 2017-08-03 | |||
| JP2015039365A | 2015-03-02 | |||
| JP2018151952A | 2018-09-27 |
Other References:
URABE, FUMIHIKO ET AL.: "Large-scale circulating microRNA profiling for the liquid biopsy of prostate cancer.", CLINICAL CANCER RESEARCH, vol. 25, no. 10, 15 May 2019 (2019-05-15), pages 3016 - 3025, XP055684095
BUDD, W. T. ET AL.: "Abstract B54: miR-125b and miR-17-3p: Newly identified tumor suppressors for prostate cancer", CANCER RESEARCH, vol. 72, no. 4, 6 February 2012 (2012-02-06), XP055684105, DOI: 10.1158/1538-7445.PRCA2012-B54
LIEB, V. ET AL.: "Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.", ONCOTARGET, vol. 9, no. 12, 13 February 2018 (2018-02-13), pages 10402 - 10416, XP055684107
SOBIN, L. ET AL., TNM CLASSIFICATION OF MALIGNANT TUMORS, vol. 7, 2010, pages 230 - 234
WOLF, AM ET AL., A CANCER JOURNAL FOR CLINICIANS, vol. 60, no. 2, 2010, pages 70 - 98
LIEB, B. ET AL., ONCOTARGET, vol. 9, no. 12, 2018, pages 10402 - 10416
FENG, S. ET AL., ONCOLOGY LETTERS, vol. 14, no. 6, 2017, pages 6943 - 6949
ZHENG ZHANG ET AL., J. COMPUT. BIOL., vol. 7, 2000, pages 203 - 214
ALTSCHUL, S.F. ET AL., JOURNAL OF MOLECULAR BIOLOGY, vol. 215, 1990, pages 403 - 410
PEARSON, W.R. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 85, pages 2444 - 2448
NIELSEN, P.E. ET AL., SCIENCE, vol. 254, 1991, pages 1497 - 500
OBIKA, S ET AL., TETRAHEDRON LETT., vol. 39, 1998, pages 5401 - 5404
BEREZIKOV E ET AL., GENOME RES., vol. 16, 2006, pages 1289 - 1298
LAGOS-QUINTANA M ET AL., RNA, vol. 9, 2003, pages 175 - 179
VOELLENKLE C ET AL., RNA, vol. 18, 2012, pages 472 - 484
LAGOS-QUINTANA M ET AL., SCIENCE, vol. 294, 2001, pages 853 - 858
LADEWIG E ET AL., GENOME RES., vol. 22, 2012, pages 1634 - 1645
BEREZIKOV E ET AL., MOL. CELL, vol. 28, 2007, pages 328 - 336
MORIN RD ET AL., GENOME RES., vol. 18, 2008, pages 610 - 621
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1993, JOHN WILLEY & SONS
SAMBROOK ET AL.: "Molecular Cloning A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
SAMBROOK, J.RUSSEL, D.: "Molecular Cloning, A LABORATORY MANUAL", vol. 1, 2, 15 January 2001, COLD SPRING HARBOR LABORATORY PRESS
RICK KAMPS ET AL., INT. J. MOL. SCI., vol. 18, no. 2, 2017, pages 308
INT. NEUROUROL. J., vol. 20, 2016, pages 76 - 83
BOLSTAD, B.M. ET AL., BIOINFORMATICS, vol. 19, 2003, pages 185 - 193
VENABLES, W.N.RIPLEY, B.D.: "Modern Applied Statistics", 2002, SPRINGER.
TAKAFUMI KANAMORI ET AL.: "Pattern Recognition", 2009, KYORITSU SHUPPAN CO., LTD.
FUREY TS. ET AL., BIOINFORMATICS., vol. 16, 2000, pages 906 - 14
C. CORTES ET AL., MACHINE LEARNING, vol. 20, 1995, pages 273 - 297
HIDEKI ASO ET AL.: "Frontier of Statistical Science", vol. 6, 2004, IWANAMI SHOTEN, PUBLISHERS, article "Statistics of pattern recognition and learning - New concepts and approaches"
NELLO CRISTIANINI ET AL.: "Introduction to SVM", 2008, KYORITSU SHUPPAN CO., LTD.
TIBSHIRANI R., J. R. STAT. SOC. SER. B, vol. 58, 1996, pages 267 - 88
YASUSHI NAGATA ET AL.: "Basics of statistical multiple comparison methods", 2007, SCIENTIST PRESS CO., LTD.
SHIMOMURA ET AL., CANCER SCIENCE, vol. 107, 2016, pages 326 - 34
See also references of EP 3835434A4
BUDD, W. T. ET AL.: "Abstract B54: miR-125b and miR-17-3p: Newly identified tumor suppressors for prostate cancer", CANCER RESEARCH, vol. 72, no. 4, 6 February 2012 (2012-02-06), XP055684105, DOI: 10.1158/1538-7445.PRCA2012-B54
LIEB, V. ET AL.: "Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.", ONCOTARGET, vol. 9, no. 12, 13 February 2018 (2018-02-13), pages 10402 - 10416, XP055684107
SOBIN, L. ET AL., TNM CLASSIFICATION OF MALIGNANT TUMORS, vol. 7, 2010, pages 230 - 234
WOLF, AM ET AL., A CANCER JOURNAL FOR CLINICIANS, vol. 60, no. 2, 2010, pages 70 - 98
LIEB, B. ET AL., ONCOTARGET, vol. 9, no. 12, 2018, pages 10402 - 10416
FENG, S. ET AL., ONCOLOGY LETTERS, vol. 14, no. 6, 2017, pages 6943 - 6949
ZHENG ZHANG ET AL., J. COMPUT. BIOL., vol. 7, 2000, pages 203 - 214
ALTSCHUL, S.F. ET AL., JOURNAL OF MOLECULAR BIOLOGY, vol. 215, 1990, pages 403 - 410
PEARSON, W.R. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 85, pages 2444 - 2448
NIELSEN, P.E. ET AL., SCIENCE, vol. 254, 1991, pages 1497 - 500
OBIKA, S ET AL., TETRAHEDRON LETT., vol. 39, 1998, pages 5401 - 5404
BEREZIKOV E ET AL., GENOME RES., vol. 16, 2006, pages 1289 - 1298
LAGOS-QUINTANA M ET AL., RNA, vol. 9, 2003, pages 175 - 179
VOELLENKLE C ET AL., RNA, vol. 18, 2012, pages 472 - 484
LAGOS-QUINTANA M ET AL., SCIENCE, vol. 294, 2001, pages 853 - 858
LADEWIG E ET AL., GENOME RES., vol. 22, 2012, pages 1634 - 1645
BEREZIKOV E ET AL., MOL. CELL, vol. 28, 2007, pages 328 - 336
MORIN RD ET AL., GENOME RES., vol. 18, 2008, pages 610 - 621
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1993, JOHN WILLEY & SONS
SAMBROOK ET AL.: "Molecular Cloning A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
SAMBROOK, J.RUSSEL, D.: "Molecular Cloning, A LABORATORY MANUAL", vol. 1, 2, 15 January 2001, COLD SPRING HARBOR LABORATORY PRESS
RICK KAMPS ET AL., INT. J. MOL. SCI., vol. 18, no. 2, 2017, pages 308
INT. NEUROUROL. J., vol. 20, 2016, pages 76 - 83
BOLSTAD, B.M. ET AL., BIOINFORMATICS, vol. 19, 2003, pages 185 - 193
VENABLES, W.N.RIPLEY, B.D.: "Modern Applied Statistics", 2002, SPRINGER.
TAKAFUMI KANAMORI ET AL.: "Pattern Recognition", 2009, KYORITSU SHUPPAN CO., LTD.
FUREY TS. ET AL., BIOINFORMATICS., vol. 16, 2000, pages 906 - 14
C. CORTES ET AL., MACHINE LEARNING, vol. 20, 1995, pages 273 - 297
HIDEKI ASO ET AL.: "Frontier of Statistical Science", vol. 6, 2004, IWANAMI SHOTEN, PUBLISHERS, article "Statistics of pattern recognition and learning - New concepts and approaches"
NELLO CRISTIANINI ET AL.: "Introduction to SVM", 2008, KYORITSU SHUPPAN CO., LTD.
TIBSHIRANI R., J. R. STAT. SOC. SER. B, vol. 58, 1996, pages 267 - 88
YASUSHI NAGATA ET AL.: "Basics of statistical multiple comparison methods", 2007, SCIENTIST PRESS CO., LTD.
SHIMOMURA ET AL., CANCER SCIENCE, vol. 107, 2016, pages 326 - 34
See also references of EP 3835434A4
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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