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Title:
KIT FOR DIAGNOSING INFECTION WITH METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) THROUGH DETECTION OF MAGNESIUM ION
Document Type and Number:
WIPO Patent Application WO/2019/132444
Kind Code:
A1
Abstract:
The present invention relates to a diagnostic kit for determining whether a subject is infected with methicillin-resistant Staphylococcus aureus (MRSA). A method of determining an infection of MRSA by using the diagnostic kit is performed by observing a change of color after a loop-mediated isothermal amplification (LAMP) reaction, and the change of color is caused by a change in magnesium concentration and may be confirmed by using a specific dye compound developed in the present invention which is sensitive to magnesium ions. According to the present invention, since amplification of MRSA DNA uses an LAMP method, the diagnostic kit provided in the present invention can be conveniently used anytime and anywhere and also enables quick diagnosis.

Inventors:
PARK JIN WOO (KR)
CHOI JAE-HO (KR)
LEE BONGKYU (KR)
KIM HYOUNG SU (KR)
KIM KIWON (KR)
LEE JAE-SUNG (KR)
JEON HYO SUNG (KR)
YUN SORA (KR)
Application Number:
KR2018/016462
Publication Date:
July 04, 2019
Filing Date:
December 21, 2018
Export Citation:
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Assignee:
BIOACTS CORP (KR)
International Classes:
C12Q1/686; C09B29/16; C09B29/28; C09B29/30; C12Q1/04; G01N33/84
Foreign References:
KR100858560B12008-09-16
KR101908869B12018-10-16
Other References:
GOTO ET AL.: "Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue", BIOTECHNIQUES, March 2009 (2009-03-01), pages 16 7 - 172, XP055032609
DIEHL ET AL.: "Azo Dyes as Indicators for Calcium and Magnesium", ANAL. CHEM., 1960, pages 1120 - 1123, XP55623612
CACHO, JUAN: "Comparative study of metallochromic indicators for magnesium", ANALYST, December 1987 (1987-12-01), pages 17 23 - 1728, XP55623617
Attorney, Agent or Firm:
CHO, Jeong Han (KR)
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