Title:
KIT AND METHOD FOR MEASURING MEASUREMENT TARGET SUBSTANCE IN BIOLOGICAL SAMPLE
Document Type and Number:
WIPO Patent Application WO/2018/181795
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a kit and method capable of accurately measuring a measurement target substance in a biological sample across a broad concentration range extending from low to high concentrations, by adequately avoiding the effect of an antibody such as an anti-serum albumin antibody in the blood. The present invention provides a kit which measures a measurement target substance in a biological sample and includes marker particles which have a first blocking agent and a first binding substance which binds to the measurement target substance, and a substrate which has a second blocking agent and a second binding substance which binds to the first binding substance or to the measurement target substance, wherein the marker particles are light-emitting marker particles containing particles and at least one type of compound represented by formula (1), and the first blocking agent and the second blocking agent differ from one another. The symbols in formula (1) are as described in the description of the present application.
Inventors:
CHIKU HIROYUKI (JP)
YOSHIOKA TOMOAKI (JP)
WATANABE KOUSUKE (JP)
HAMADA KAZUHIRO (JP)
SASAKI KOUITSU (JP)
YOSHIOKA TOMOAKI (JP)
WATANABE KOUSUKE (JP)
HAMADA KAZUHIRO (JP)
SASAKI KOUITSU (JP)
Application Number:
PCT/JP2018/013405
Publication Date:
October 04, 2018
Filing Date:
March 29, 2018
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
G01N33/543; C07F5/02; C09K11/06
Domestic Patent References:
| WO2015129361A1 | 2015-09-03 | |||
| WO2017150516A1 | 2017-09-08 | |||
| WO2018021377A1 | 2018-02-01 |
Foreign References:
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Other References:
SUDA, Y. ET AL.: "Multi-thiophene-substituted NIR boron-dibenzopyrromethene dyes: synthesis and their spectral properties", TETRAHEDRON, vol. 71, 2015, pages 4174 - 4182, XP029155366, DOI: doi:10.1016/j.tet.2015.04.094
WANG, J. ET AL.: "Synthesis, structure and photophysical properties ofnear-infrared 3, 5-diarylbenzoBODIPY fluorophores", RSC ADVANCES, vol. 6, no. 57, 2016, pages 52180 - 52188, XP055457453, DOI: doi:10.1039/C6RA04412C
MACROMOLECULES, vol. 43, 2010, pages 193 - 200
"Bioorganic & Medicinal Chemistry", vol. 12, 2004, pages: 2079 - 2098
"The Immunoassay Handbook", 2005
See also references of EP 3605094A4
WANG, J. ET AL.: "Synthesis, structure and photophysical properties ofnear-infrared 3, 5-diarylbenzoBODIPY fluorophores", RSC ADVANCES, vol. 6, no. 57, 2016, pages 52180 - 52188, XP055457453, DOI: doi:10.1039/C6RA04412C
MACROMOLECULES, vol. 43, 2010, pages 193 - 200
"Bioorganic & Medicinal Chemistry", vol. 12, 2004, pages: 2079 - 2098
"The Immunoassay Handbook", 2005
See also references of EP 3605094A4
Attorney, Agent or Firm:
SIKS & CO. (JP)
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