Title:
KIT AND METHOD FOR MEASURING MEASUREMENT TARGET SUBSTANCE IN BIOLOGICAL SAMPLE
Document Type and Number:
WIPO Patent Application WO/2018/181800
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a kit and method capable of accurately measuring a measurement target substance in a biological sample across a broad concentration range extending from low to high concentrations. The present invention provides a kit which measures a measurement target substance in a biological sample and includes marker particles which have a first blocking agent and a first binding substance which binds to the measurement target substance in the biological sample, and a substrate which has a second blocking agent and a second binding substance which binds to the first binding substance or to the measurement target substance, wherein the marker particles are light-emitting marker particles containing particles and at least one type of compound represented by formula (1), and the first blocking agent and the second blocking agent differ from one another. The symbols in formula (1) are as described in the description of the present application.
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Inventors:
CHIKU HIROYUKI (JP)
WATANABE KOUSUKE (JP)
KANEKO KAZUHEI (JP)
HAMADA KAZUHIRO (JP)
SASAKI KOUITSU (JP)
YOSHIOKA TOMOAKI (JP)
HANAKI NAOYUKI (JP)
WATANABE KOUSUKE (JP)
KANEKO KAZUHEI (JP)
HAMADA KAZUHIRO (JP)
SASAKI KOUITSU (JP)
YOSHIOKA TOMOAKI (JP)
HANAKI NAOYUKI (JP)
Application Number:
PCT/JP2018/013410
Publication Date:
October 04, 2018
Filing Date:
March 29, 2018
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
G01N33/543; C07F5/02; C09K11/06; G01N21/64; G01N21/78
Domestic Patent References:
| WO2015129361A1 | 2015-09-03 | |||
| WO2017150516A1 | 2017-09-08 | |||
| WO2018038138A1 | 2018-03-01 |
Foreign References:
| JP2016057145A | 2016-04-21 | |||
| US20110054187A1 | 2011-03-03 | |||
| CN1944540A | 2007-04-11 | |||
| JPH07508309A | 1995-09-14 | |||
| JP2008527332A | 2008-07-24 | |||
| JP3442777B2 | 2003-09-02 | |||
| JP2014235081A | 2014-12-15 | |||
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| JP2000206115A | 2000-07-28 | |||
| JP2008249361A | 2008-10-16 | |||
| JP2010190880A | 2010-09-02 |
Other References:
XU, JUNCHAO ET AL.: "meso-C6F5 substituted BODIPYs with distinctive spectroscopic properties and their application for bioimaging in living cells", TETRAHEDRON, vol. 70, no. 35, 2014, pages 5800 - 5805, XP029038855
HECHT, MANDY ET AL.: "Fluorinated Boron-Dipyrromethene (BODIPY) Dyes: Bright and Versatile Probes for Surface Analysis", CHEMISTRYOPEN, vol. 2, February 2013 (2013-02-01), pages 25 - 38, XP055466454
OLIVIER GALANGAU ET AL., ORG. BIOMOL. CHEM., vol. 8, 2010, pages 4546 - 4553
MACROMOLECULES, vol. 43, 2010, pages 193 - 200
"The Immunoassay Handbook", 2005
See also references of EP 3605093A4
HECHT, MANDY ET AL.: "Fluorinated Boron-Dipyrromethene (BODIPY) Dyes: Bright and Versatile Probes for Surface Analysis", CHEMISTRYOPEN, vol. 2, February 2013 (2013-02-01), pages 25 - 38, XP055466454
OLIVIER GALANGAU ET AL., ORG. BIOMOL. CHEM., vol. 8, 2010, pages 4546 - 4553
MACROMOLECULES, vol. 43, 2010, pages 193 - 200
"The Immunoassay Handbook", 2005
See also references of EP 3605093A4
Attorney, Agent or Firm:
SIKS & CO. (JP)
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