Title:
KLUYVEROMYCES MARXIANUS STRAIN HAVING BLOCKED ETHANOL PRODUCTION PATHWAY, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/003439
Kind Code:
A1
Abstract:
The present invention relates to a Kluyveromyces marxianus strain which is a Crabtree-negative yeast in which the pyruvate decarboxylase is inactivated in order to prevent ethanol fermentation, and to a yeast strain for producing various organic acids by introducing various exogenous genes to the Kluyveromyces marxianus strain. Further, the present invention relates to a method for producing lactic acids by culturing the strain. The mutant strain in which the pyruvate decarboxylase is inactivated according to the present invention does not produce ethanol during the production of lactic acids. The method of the present invention effectively produces organic acids through the strain that produces organic acids by introducing various exogenous genes to the strain.
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Inventors:
SOHN JUNG HOON (KR)
KIM HYUN JIN (KR)
BAE JUNG HOON (KR)
SUNG BONG HYUN (KR)
KIM CHUL HO (KR)
LEE SEUNG GOO (KR)
KIM HYUN JIN (KR)
BAE JUNG HOON (KR)
SUNG BONG HYUN (KR)
KIM CHUL HO (KR)
LEE SEUNG GOO (KR)
Application Number:
PCT/KR2013/005661
Publication Date:
January 03, 2014
Filing Date:
June 26, 2013
Export Citation:
Assignee:
KOREA RES INST OF BIOSCIENCE (KR)
International Classes:
C12N1/19; C12N15/53; C12N15/60
Domestic Patent References:
| WO2007117282A2 | 2007-10-18 |
Foreign References:
| US20060110810A1 | 2006-05-25 | |||
| US20050112737A1 | 2005-05-26 | |||
| US20090081793A1 | 2009-03-26 | |||
| US20030228671A1 | 2003-12-11 | |||
| US7943366B2 | 2011-05-17 |
Other References:
DATABASE NCBI, GENBANK 14 November 2005 (2005-11-14), accession no. Q225115.1
DATABASE NCBI, GENBANK 11 May 2011 (2011-05-11), accession no. R774011.1
DATABASE NCBI, GENBANK 11 May 2011 (2011-05-11), accession no. R774011.1
Attorney, Agent or Firm:
SON, MIN (KR)
손민 (KR)
손민 (KR)
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