Title:
KRAS G12D INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2022/262686
Kind Code:
A1
Abstract:
Disclosed are novel compounds which are KRAS G12D inhibitors, their synthesis and their use for treating diseases or conditions, such as cancer, and in particular for inhibiting the activity of KRAS G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.
Inventors:
HAN YING (CN)
LI DAPENG (CN)
WANG TONG (CN)
LI DAPENG (CN)
WANG TONG (CN)
Application Number:
PCT/CN2022/098467
Publication Date:
December 22, 2022
Filing Date:
June 13, 2022
Export Citation:
Assignee:
JINGRUI BIOPHARMA CO LTD (CN)
International Classes:
A61K31/4353; A61K31/439; A61K31/517; A61P35/00; C07D239/80; C07D403/14; C07D471/02; C07D487/04; C07D519/00
Domestic Patent References:
| WO2021041671A1 | 2021-03-04 | |||
| WO2022002102A1 | 2022-01-06 | |||
| WO2022042630A1 | 2022-03-03 | |||
| WO2022061251A1 | 2022-03-24 | |||
| WO2022068921A1 | 2022-04-07 | |||
| WO2022098625A1 | 2022-05-12 | |||
| WO2022105859A1 | 2022-05-27 |
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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