LABELED MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS FOR IMAGING ATHEROSCLEROSIS AND VULNERABLE PLAQUE

Title:

LABELED MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS FOR IMAGING ATHEROSCLEROSIS AND VULNERABLE PLAQUE

Document Type and Number:

WIPO Patent Application WO2002067761

Kind Code:

A3

Abstract:

Detectably labeled macrophage scavenger receptor antagonists useful for the diagnosis and monitoring of various cardiovascular diseases including but not limited to atherosclerosis, vulnerable plaque, coronary artery disease, renal disease, thrombosis, transient ischemia due to clotting, stroke, myocardial infarction, organ transplant, organ failure and hypercholesterolemia.

Inventors:

EDWARDS D SCOTT
LIU SHUANG

Application Number:

PCT/US2002/005156

Publication Date:

February 13, 2003

Filing Date:

February 22, 2002

Export Citation:

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Assignee:

BRISTOL MYERS SQUIBB PHARMA CO (US)

International Classes:

A61K9/08; A61K47/10; C07D213/89; A61K47/12; A61K47/18; A61K47/20; A61K47/22; A61K47/46; A61K49/00; A61K49/04; A61K51/00; A61K51/04; C07C235/64; C07F1/08; C07F13/00; (IPC1-7): A61K51/00; A61M36/14

Foreign References:

US4577042A

1986-03-18

Other References: