Title:
β-LACTAMASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2019/221122
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a compound having a β-lactamase inhibitory activity. The problem is solved by a compound which is represented by general formula (1) that represents a compound in which a specific location of a 5-membered ring having flatness is substituted with a sulfamoyl group and a carboxyl group.
Inventors:
ARAKAWA YOSHICHIKA (JP)
WACHINO JUN-ICHI (JP)
KIMURA KOUJI (JP)
JIN WAN CHUN (JP)
SATO AYATO (JP)
WACHINO JUN-ICHI (JP)
KIMURA KOUJI (JP)
JIN WAN CHUN (JP)
SATO AYATO (JP)
Application Number:
PCT/JP2019/019133
Publication Date:
November 21, 2019
Filing Date:
May 14, 2019
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
International Classes:
A61K31/341; A61K31/381; A61K31/40; A61K45/00; A61P31/04; A61P43/00; C07D207/36; C07D307/68
Domestic Patent References:
| WO2003070682A1 | 2003-08-28 | |||
| WO2013180197A1 | 2013-12-05 |
Foreign References:
| JP2016520658A | 2016-07-14 | |||
| JP2015155435A | 2015-08-27 | |||
| JP2015512440A | 2015-04-27 |
Other References:
RACHEL, A. ET AL.: "Structure-Based Discovery of a Novel", NONCOVALENT INHIBITOR OF AMPC BETA-LACTAMASE, STRUCTURE, vol. 10, no. 7, 2002, pages 1013 - 1023, XP009524466, DOI: 10.1016/S0969-2126(02)00799-2
See also references of EP 3795149A4
See also references of EP 3795149A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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