Title:
LACTIC ACID BACTERIUM HAVING PURINE BODY UPTAKE ABILITY, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/080371
Kind Code:
A1
Abstract:
Provided is a method for obtaining a lactic acid bacterium having a property of reducing a serum uric acid level. The present invention relates to: a method for screening for a lactic acid bacterium, which comprises determining the amount of a purine body incorporated in each of lactic acid bacteria in a culture medium containing the purine body and then screening for a lactic acid bacterium having a property of trapping the purine body among the lactic acid bacteria employing the amount as a measure; and a purine body trapping agent for reducing a serum uric acid level, which comprises a lactic acid bacterium obtained by the method.
Inventors:
YAMADA NARUOMI (JP)
KANO HIROSHI (JP)
IWAMOTO CHIZURU (JP)
OHSHIBA YUKIO (JP)
TSUBOI HIROSHI (JP)
ASAMI YUKIO (JP)
ITOU HIROYUKI (JP)
KANO HIROSHI (JP)
IWAMOTO CHIZURU (JP)
OHSHIBA YUKIO (JP)
TSUBOI HIROSHI (JP)
ASAMI YUKIO (JP)
ITOU HIROYUKI (JP)
Application Number:
PCT/JP2015/082188
Publication Date:
May 26, 2016
Filing Date:
November 17, 2015
Export Citation:
Assignee:
MEIJI CO LTD (JP)
International Classes:
C12N1/00; A23L33/10; A61K35/747; A61P3/00; C12N1/20
Domestic Patent References:
| WO2009069704A1 | 2009-06-04 | |||
| WO2009069219A1 | 2009-06-04 | |||
| WO2004112809A1 | 2004-12-29 |
Foreign References:
| JP2008005834A | 2008-01-17 |
Other References:
LI, M. ET AL.: "Screening and Characterization of Purine Nucleoside Degrading Lactic Acid Bacteria Isolated from Chinese Sauerkraut and Evaluation of the Serum Uric Acid Lowering Effect in Hyperuricemic Rats", PLOS ONE, vol. 9, no. 9, pages e105577
MCLEOD, A. ET AL.: "Global transcriptome response in Lactobacillus sakei during growth on ribose", BMC MICROBIOLOGY, vol. 11, no. 145, 2011, pages 1 - 26
FORET, M. ET AL.: "Interconversion and Uptake of Nucleotides, Nucleosides, and Purine Bases by the Marine Bacterium MB22", J. BACTERIOL., vol. 150, no. 2, 1982, pages 471 - 482
"Press release, Purine-tai ni Sayo suru Aratana Probiotics Nyusankin 'PA-3 Kabu' o Hakken", 27 March 2015 (2015-03-27), Retrieved from the Internet [retrieved on 20151209]
YAMADA, N. ET AL.: "Selection of Lactobacillus gasseri strain which has high ability in metabolizing purine", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
NARUOMI YAMADA ET AL.: "Chokan kara Kyushu sareru Purine-tai o Teigen suru Nyusankin", MILK SCIENCE, vol. 64, no. 2, 25 August 2015 (2015-08-25), pages 172
KILSTRUP, M. ET AL.: "Nucleotide metabolism and its control in lactic acid bacteria", FEMS MICROBIOL. REV., vol. 29, 2005, pages 555 - 590
JUN OGAWA ET AL.: "Nyusankin Taisha to Oishii Kenko Seikatsu", JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, vol. 91, no. 11, 2013, Japan, pages 637 - 640
TAKESHI IKENAGA ET AL.: "Takai Purine Nucleoside Taishano o Yusuru Nyusankin no Shokujisei Konyosankessho Model Rat no Kecchu Nyosanchi ni Oyobosu Eikyo", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 58, 2004, pages 318
ROY-BURMAN, S ET AL.: "Transport of Purines and Deoxyadenosine in Escherichia coli", J. BIOL. CHEM., vol. 250, no. 24, 1975, pages 9270 - 9275
MCLEOD, A. ET AL.: "Global transcriptome response in Lactobacillus sakei during growth on ribose", BMC MICROBIOLOGY, vol. 11, no. 145, 2011, pages 1 - 26
FORET, M. ET AL.: "Interconversion and Uptake of Nucleotides, Nucleosides, and Purine Bases by the Marine Bacterium MB22", J. BACTERIOL., vol. 150, no. 2, 1982, pages 471 - 482
"Press release, Purine-tai ni Sayo suru Aratana Probiotics Nyusankin 'PA-3 Kabu' o Hakken", 27 March 2015 (2015-03-27), Retrieved from the Internet
YAMADA, N. ET AL.: "Selection of Lactobacillus gasseri strain which has high ability in metabolizing purine", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
NARUOMI YAMADA ET AL.: "Chokan kara Kyushu sareru Purine-tai o Teigen suru Nyusankin", MILK SCIENCE, vol. 64, no. 2, 25 August 2015 (2015-08-25), pages 172
KILSTRUP, M. ET AL.: "Nucleotide metabolism and its control in lactic acid bacteria", FEMS MICROBIOL. REV., vol. 29, 2005, pages 555 - 590
JUN OGAWA ET AL.: "Nyusankin Taisha to Oishii Kenko Seikatsu", JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, vol. 91, no. 11, 2013, Japan, pages 637 - 640
TAKESHI IKENAGA ET AL.: "Takai Purine Nucleoside Taishano o Yusuru Nyusankin no Shokujisei Konyosankessho Model Rat no Kecchu Nyosanchi ni Oyobosu Eikyo", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 58, 2004, pages 318
ROY-BURMAN, S ET AL.: "Transport of Purines and Deoxyadenosine in Escherichia coli", J. BIOL. CHEM., vol. 250, no. 24, 1975, pages 9270 - 9275
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
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