Title:
LACTIC ACID BACTERIUM, INTERLEUKIN-22 PRODUCTION INDUCING AGENT, SKIN BARRIER FUNCTION ENHANCING AGENT
Document Type and Number:
WIPO Patent Application WO/2019/160115
Kind Code:
A1
Abstract:
Provided is a lactic acid bacterium that has the ability to improve the viability of B cells and the ability to activate B cells, and induces production of interleukin-22. The lactic acid bacterium has the ability to improve the viability of B cells and the ability to activate B cells, and induces production of interleukin-22.
Inventors:
KUMAZAWA TOSHIHIKO (JP)
NISHIMURA ATSUHISA (JP)
ASAI NORIYUKI (JP)
ADACHI TAKAHIRO (JP)
NISHIMURA ATSUHISA (JP)
ASAI NORIYUKI (JP)
ADACHI TAKAHIRO (JP)
Application Number:
PCT/JP2019/005692
Publication Date:
August 22, 2019
Filing Date:
February 15, 2019
Export Citation:
Assignee:
ICHIBIKI CO LTD (JP)
UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP)
UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP)
International Classes:
C12N1/20; A61K35/742; A61K35/744; A61K35/747; A61P17/16; A61P43/00
Domestic Patent References:
| WO2018047979A1 | 2018-03-15 |
Other References:
"Ichibiki's New Brand", THE JAPAN FOOD JOURNAL, 21 August 2017 (2017-08-21)
"Adaptgen Pharmaceutical launches Miso-Derivated Lactobacillus OEM: Confirming weight loss effects", THE CHEMICAL DAILY CO., 24 October 2016 (2016-10-24)
YANG, GUI-YAN ET AL.: "Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the I1-22BP/ IL -22/STAT3 Pathway", FRONT. CELL . INFECT. MICROBIOL., vol. 7, 2017, pages 1 - 16
NAKAMOTO, NOBUHIRO ET AL.: "Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice", CELL REP., vol. 21, no. 5, 31 October 2017 (2017-10-31), pages 1215 - 1226, XP055634898
QIU, YUEQIN ET AL.: "Lactobacillus plantarum Enhanced 11-22 Production in Natural Killer (NK) cells That Protect the Integrity of Intestinal Epithelial Cell Barrier Damaged by Enterotoxigenic Escherichia coli", INT. J. MOL. SCI., vol. 18, no. 11, 13 November 2017 (2017-11-13), pages 1 - 15, XP055634899
MAJEED, MUHAMMED ET AL.: "Role of probiotics for balanced skin microflora", EURO COSMETICS, vol. 7, 2015, pages 10 - 11, XP055634588
KUMAZAWA, TOSHIHIKO ET AL.: "Isolation of Immune-regulatory Tetragenococcus halophilus from miso", PLOS ONE, vol. 13, no. 12, 26 December 2018 (2018-12-26), pages e0208821, XP055634901
"Adaptgen Pharmaceutical launches Miso-Derivated Lactobacillus OEM: Confirming weight loss effects", THE CHEMICAL DAILY CO., 24 October 2016 (2016-10-24)
YANG, GUI-YAN ET AL.: "Oral Administration of Lactobacillus rhamnosus GG Ameliorates Salmonella Infantis-Induced Inflammation in a Pig Model via Activation of the I1-22BP/ IL -22/STAT3 Pathway", FRONT. CELL . INFECT. MICROBIOL., vol. 7, 2017, pages 1 - 16
NAKAMOTO, NOBUHIRO ET AL.: "Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice", CELL REP., vol. 21, no. 5, 31 October 2017 (2017-10-31), pages 1215 - 1226, XP055634898
QIU, YUEQIN ET AL.: "Lactobacillus plantarum Enhanced 11-22 Production in Natural Killer (NK) cells That Protect the Integrity of Intestinal Epithelial Cell Barrier Damaged by Enterotoxigenic Escherichia coli", INT. J. MOL. SCI., vol. 18, no. 11, 13 November 2017 (2017-11-13), pages 1 - 15, XP055634899
MAJEED, MUHAMMED ET AL.: "Role of probiotics for balanced skin microflora", EURO COSMETICS, vol. 7, 2015, pages 10 - 11, XP055634588
KUMAZAWA, TOSHIHIKO ET AL.: "Isolation of Immune-regulatory Tetragenococcus halophilus from miso", PLOS ONE, vol. 13, no. 12, 26 December 2018 (2018-12-26), pages e0208821, XP055634901
Attorney, Agent or Firm:
WATANABE Kazuhira (JP)
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