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Title:
LACTOBACILLUS CRISPATUS KBL693 STRAIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/226002
Kind Code:
A1
Abstract:
The present invention relates to a Lactobacillus crispatus KBL693 strain and a use thereof. The Lactobacillus crispatus KBL693 (accession number KCTC 13519BP) strain according to the present invention attenuates allergic responses of cells and significantly improves symptoms of atopic dermatitis, with the concomitant exhibition of anti-inflammatory and anti-fungal effects. Thus, the single strain alone can achieve all the purposes of alleviating atopic dermatitis and other allergic diseases, inflammatory diseases, and autoimmune diseases, thereby finding advantageous applications as a probiotic substance. In addition, based on the antifungal activity thereof, the strain can be advantageously utilized in a skin topical agent against various skin diseases caused by fungi and in a cosmetic composition and a functional patch for alleviating sensitive skin.

Inventors:
KO, Woo Ri (mirine 202, 26 Inheon 12-gil,,Gwanak-Gu, Seoul, 08797, KR)
LEE, June Chul (301 46-4, Majinbae 4-gil Seojong-myeon,,Yangpyeong-Gun, Gyeonggi-do, 12502, KR)
NAM, Tae Wook (3-3 Seopangyo-ro 66beon-gil, Bundang-Gu, Seongnam-Si, Gyeonggi-do, 13479, KR)
KO, Gwang Pyo (A-1307, 57 Hyoryeong-ro 72-gil,,Seocho-Gu, Seoul, 06732, KR)
YOU, Hyun Ju (2-102, 25 Seoksan-ro 169beon-gil,Namdong-gu, Incheon, 21545, KR)
YOON, So Yon (9 Pangyo-ro 197beon-gil, Bundang-gu Seongnam-si, Gyeonggi-do, 13473, KR)
SONG, Seok Cheon (205 50, Gwanak-ro 11-gil Gwanak-gu, Seoul, 08832, KR)
Application Number:
KR2019/006231
Publication Date:
November 28, 2019
Filing Date:
May 23, 2019
Export Citation:
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Assignee:
KO BIOLABS, INC. (220-628, 1 Gwanak-ro,,Gwanak-Gu, Seoul, 08826, KR)
SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (1 Gwanak-ro, Gwanak-gu, Seoul, 08826, KR)
International Classes:
C12N1/20; A23L33/135; A61K35/747; A61P17/00; A61P27/14; A61P29/00; C12R1/225
Attorney, Agent or Firm:
LEE & KO IP (3F 63, Namdaemun-ro,Jung-Gu, Seoul, 04532, KR)
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